A wide body of evidence suggests that voltage-gated sodium channels (VGSCs) are
expressed de novo in several human carcinomas where channel activity promotes a variety …

Voltage-gated sodium channels (VGSCs) are transmembrane proteins which function as
gates that control the flux of ions across the cell membrane. They are key ion channels for …

Loss of epithelial polarity and gain in invasiveness by carcinoma cells are critical events in
the aggressive progression of cancers and depend on phenotypic transition programs such …

Voltage-gated sodium (Na V) channels, initially characterized in excitable cells, have been
shown to be aberrantly expressed in non-excitable cancer tissues and cells from epithelial …

During the second half of the last century, the prevalent knowledge recognized the voltage-
gated sodium channels (VGSCs) as the proteins responsible for the generation and …

The incidence of thyroid cancer remains high worldwide, and papillary thyroid cancer (PTC)
is the most common type. Potassium Calcium-Activated Channel Subfamily N Member 4 …

Several superfamilies of plasma membrane channels which regulate transmembrane ion
flux have also been shown to regulate a multitude of cellular processes, including …

Background Thermal ablation (TA), as an alternative to surgery, has shown some benefits in
the treatment of papillary thyroid microcarcinoma (PTMC) patients, especially for those who …

Follicular thyroid carcinoma (FTC) is one of the most common malignant tumors of the
endocrine system. Recent studies have shown that voltage-gated sodium channels (VGSCs) …

Homeobox protein Emx2 is a transcription factor that is encoded by the EMX2 gene. In this
study, using data from the Cancer Genome Atlas-Thyroid Cancer (TCGA-THCA), we aimed …