Chronic obstructive pulmonary disease in never-smokers: risk factors, pathogenesis, and implications for prevention and treatment
IA Yang, CR Jenkins, SS Salvi - The Lancet Respiratory Medicine, 2022 - thelancet.com
Chronic obstructive pulmonary disease (COPD) was traditionally thought to be caused by
tobacco smoking. However, recognition of the importance of non-smoking-related risk …
tobacco smoking. However, recognition of the importance of non-smoking-related risk …
[HTML][HTML] The pathology of small airways disease in COPD: historical aspects and future directions
A Higham, AM Quinn, JED Cançado, D Singh - Respiratory research, 2019 - Springer
Small airways disease (SAD) is a cardinal feature of chronic obstructive pulmonary disease
(COPD) first recognized in the nineteenth century. The diverse histopathological features …
(COPD) first recognized in the nineteenth century. The diverse histopathological features …
[HTML][HTML] Definition and nomenclature of chronic obstructive pulmonary disease: time for its revision
Attempts to define concepts and things date back to the time of Aristotle, around 2,400 years
ago, when he proposed that a definition should state the essential nature or being of …
ago, when he proposed that a definition should state the essential nature or being of …
[HTML][HTML] Global initiative for chronic obstructive lung disease 2023 report: GOLD executive summary
The Global Initiative for Chronic Obstructive Lung Disease (GOLD) has published the
complete 2023 GOLD report, which can be freely downloaded from its web page (www …
complete 2023 GOLD report, which can be freely downloaded from its web page (www …
[HTML][HTML] From GOLD 0 to pre-COPD
The diagnosis of chronic obstructive pulmonary disease (COPD) currently requires the
demonstration of poorly reversible airflow limitation, defined as a post-bronchodilator …
demonstration of poorly reversible airflow limitation, defined as a post-bronchodilator …
Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort
G Radicioni, A Ceppe, AA Ford, NE Alexis… - The Lancet …, 2021 - thelancet.com
Background We previously described the contributions of increased total airway mucin
concentrations to the pathogenesis and diagnosis of the chronic bronchitic component of …
concentrations to the pathogenesis and diagnosis of the chronic bronchitic component of …
Advances in chronic obstructive pulmonary disease
MC Ferrera, WW Labaki, MLK Han - Annual review of medicine, 2021 - annualreviews.org
Chronic obstructive pulmonary disease (COPD) is a common respiratory disorder with
significant morbidity and mortality. Despite its prevalence, COPD is underdiagnosed, and …
significant morbidity and mortality. Despite its prevalence, COPD is underdiagnosed, and …
Lung microbiota and metabolites collectively associate with clinical outcomes in milder stage chronic obstructive pulmonary disease
SS Madapoosi, C Cruickshank-Quinn… - American journal of …, 2022 - atsjournals.org
Rationale: Chronic obstructive pulmonary disease (COPD) is variable in its development.
Lung microbiota and metabolites collectively may impact COPD pathophysiology, but …
Lung microbiota and metabolites collectively may impact COPD pathophysiology, but …
Chronic obstructive pulmonary disease biomarkers and their interpretation
RA Stockley, DMG Halpin, BR Celli… - American journal of …, 2019 - atsjournals.org
The pathology and impact of chronic obstructive pulmonary disease (COPD) results from an
abnormal inflammatory process resulting in tissue damage with ineffective repair in …
abnormal inflammatory process resulting in tissue damage with ineffective repair in …
[HTML][HTML] Regenerative metaplastic clones in COPD lung drive inflammation and fibrosis
Chronic obstructive pulmonary disease (COPD) is a progressive condition of chronic
bronchitis, small airway obstruction, and emphysema that represents a leading cause of …
bronchitis, small airway obstruction, and emphysema that represents a leading cause of …