Osteoarthritis is a common age-related joint degenerative disease. Pain, swelling, brief
morning stiffness, and functional limitations are its main characteristics. There are still no …

Osteoarthritis (OA) is a multifactorial chronic disease primarily characterized by the
degeneration of articular cartilage. Currently, there is a lack of effective treatments for OA …

Subtalar osteoarthritis (STOA) is often secondary to chronic ankle sprains, which seriously
affects the quality of life of patients. Due to its etiology and pathogenesis was not studied …

Dopamine (DA) is a crucial neurotransmitter that plays an important role in maintaining
physiological function in human body. In the past, most studies focused on the relationship …

Introduction This study develops assays to quantify collagen subtypes and crosslinks with
liquid chromatography-mass spectrometry (LC-MS) and characterizes the cartilages in the …

The functional relevance and mechanistic basis of the effects of the neurotransmitter
dopamine (DA) on inflammation remain unclear. Here we reveal that DA inhibited TLR2 …

Osteoarthritis (OA), a common degenerative joint disease, is characterized by the
progressive degradation of articular cartilage and inflammation. Hederagenin (HE) is a …

Fucoidan has been reported to have a variety of biological activities. However, different
algae species, extraction methods, harvesting seasons, and growth regions lead to the …

Objective This study aimed to identify the hub genes and pathways of genes related to
oxidative stress of cartilage in osteonecrosis of femoral head (ONFH), and to predict the …

Owing to the limited healing ability, the repair of meniscal injury and prevention of secondary
osteoarthritis pose considerable challenges for clinicians and researchers. While tissue …