Interleukin-33 (IL-33) is a member of the interleukin-1 (IL-1) family that is expressed in the
nuclei of endothelial and epithelial cells of barrier tissues, among others. It functions as an …

Simple Summary Lung cancer is currently the second leading cause of cancer death
worldwide. Cytokines are small proteins that carry messages between cells and are known …

Interleukins (ILs) are signaling molecules that are crucial in regulating immune responses
during infectious diseases. Pro-inflammatory ILs contribute to the activation and recruitment …

Interleukin-33 (IL-33) functions both as a secreted cytokine and as a nuclear factor, with
pleiotropic roles in cancer and immunity. Here, we explored its role in hepatocellular …

ABSTRACT IL-37 is a member of the IL-1 superfamily exerting anti-inflammatory functions in
a number of diseases. Extracellular IL-37 triggers the inhibitory receptor IL-1R8 that is …

Inflammation is required for protective responses against pathogens and is thus essential for
survival, but sustained inflammation can lead to diseases, such as atherosclerosis and …

Inflammation, especially chronic inflammation, is closely linked to tumor development. As
essential chronic inflammatory cytokines, the interleukin family plays a key role in …

Chronic diseases are persistent health conditions that affect a large number of patients
worldwide and have serious implications on the health status of patients, representing a …

Interleukin-37 (IL-37) is a newly discovered member of IL-1 family. The cytokine was proved
to have extensive protective effects in infectious diseases, allergic diseases, metabolic …

Abstract Interleukin-38 (IL-38) is the most recent member of the IL-1 family that acts as a
natural inflammatory inhibitor by binding to cognate receptors, particularly the IL-36 receptor …