Advances in pharmacotherapies for hyperuricemia

F Piani, D Agnoletti, C Borghi - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Hyperuricemia is an overlooked cardiovascular and renal risk factor.
Epidemiological and genetic studies have shown an independent role of uric acid in the risk …

Impact of Hyperuricemia and Urate-Lowering Agents on Cardiovascular Diseases

F Sosa, M Shaban, J Lopez, GJ Duarte… - Clinical Medicine …, 2024 - journals.sagepub.com
The association between hyperuricemia and cardiovascular diseases has been studied for
many years. Research has shown a link between high uric acid levels and increased risk of …

Serum uric acid is associated with chronic kidney disease in elderly Chinese patients with diabetes

Q Zhou, S Ke, Y Yan, Y Guo, Q Liu - Renal Failure, 2023 - Taylor & Francis
Background The relationship between hyperuricemia and chronic kidney disease (CKD) has
been investigated extensively. However, studies on elderly individuals are still limited …

[HTML][HTML] Characterizing the follicular fluid metabolome: quantifying the correlation across follicles and differences with the serum metabolome

RB Hood, D Liang, Y Tan, J Ford, I Souter, DP Jones… - Fertility and sterility, 2022 - Elsevier
Objective To compare the variability in metabolomes between the serum and follicular fluid,
as well as across 3 dominant follicles. Design Prospective cohort study. Setting An academic …

Are serum uric acid levels predictors of cardiovascular risk? An update

M Georgoulis, DP Mikhailidis… - Current Opinion in …, 2023 - journals.lww.com
There is evidence supporting that elevated serum uric acid levels are positively associated
with cardiovascular disease risk and might represent a useful additional marker for risk …

Novel pathological implications of serum uric acid with cardiovascular disease risk in obesity

D Wakabayashi, S Kato, M Tanaka… - Diabetes Research and …, 2023 - Elsevier
Aims This cohort study intended to elucidate the association between serum uric acid (SUA)
levels and cardiovascular disease events in Japanese patients with obesity. Methods …

[HTML][HTML] Temporal changes in serum uric acid and risk for metabolic syndrome: a longitudinal cohort study

X Feng, Y Guo, H Tu, S Li, C Chen, M Sun… - Diabetology & Metabolic …, 2022 - Springer
Background Studies suggested elevated serum uric acid (SUA) levels are associated with
metabolic syndrome (MetS). However, it remains unclear whether baseline SUA and …

Uric acid plasma levels are associated with C-reactive protein concentrations and the extent of coronary artery lesions in patients with acute coronary syndromes

G Cimmino, E Gallinoro, L di Serafino… - Internal and Emergency …, 2023 - Springer
Many studies have pointed out that inflammation plays a pivotal role in pathophysiology of
acute coronary syndromes (ACS) because several inflammatory molecules impair the …

Gout flares and intercritical gout: do they play a significant role in predicting cardiovascular events?

DP Mikhailidis, M Kouvari… - Current Vascular …, 2022 - ingentaconnect.com
CONCLUSION Clearly the clinical relevance of subclinical MSU crystal deposits needs to be
determined. This should include asymptomatic hyperuricaemia. It may be that decreasing …

Diagnostic Value of Serum Galectin-3 Binding Protein Level in Patients with Pulmonary Arterial Hypertension

M Li, W Pan, D Tian, D Chen, X Zhang… - Current Vascular …, 2023 - ingentaconnect.com
Background: Pulmonary arterial hypertension (PAH) still lacks effective biomarkers to assist
in its diagnosis and prognosis. Galectin-3 binding protein (Gal-3BP) plays a role in immune …