Reproducibility evaluation of urinary peptide detection using CE-MS
In recent years, capillary electrophoresis coupled to mass spectrometry (CE-MS) has been
increasingly applied in clinical research especially in the context of chronic and age …
increasingly applied in clinical research especially in the context of chronic and age …
Collagen-derived peptides in CKD: a link to fibrosis
Collagen is a major component of the extracellular matrix (ECM) and has an imminent role
in fibrosis, in, among others, chronic kidney disease (CKD). Collagen alpha-1 (I)(col1a1) is …
in fibrosis, in, among others, chronic kidney disease (CKD). Collagen alpha-1 (I)(col1a1) is …
Urinary peptidomic liquid biopsy for non-invasive differential diagnosis of chronic kidney disease
Background and hypothesis Specific urinary peptides hold information on disease
pathophysiology, which, in combination with artificial intelligence, could enable non-invasive …
pathophysiology, which, in combination with artificial intelligence, could enable non-invasive …
Discovery of Fibrinogen γ-chain as a potential urinary biomarker for renal interstitial fibrosis in IgA nephropathy
J Guan, M Wang, M Zhao, W Ni, M Zhang - BMC nephrology, 2023 - Springer
Abstract Background IgA nephropathy (IgAN) is a major cause of chronic kidney disease
(CKD). Renal interstitial fibrosis is a hallmark of CKD progression. Non-invasive biomarkers …
(CKD). Renal interstitial fibrosis is a hallmark of CKD progression. Non-invasive biomarkers …
Comparative proteomic analysis of children FSGS FFPE tissues
J Ni, S Tian, L Bai, Q Lv, J Liu, J Liu, Y Fang, Y Zhai… - BMC pediatrics, 2022 - Springer
Background In children, focal segmental glomerulosclerosis (FSGS) is the main cause of
steroid resistant nephrotic syndrome (SRNS). To identify specific candidates and the …
steroid resistant nephrotic syndrome (SRNS). To identify specific candidates and the …
Minimal Change Disease: Pathogenetic Insights from Glomerular Proteomics
AA Bărar, IE Pralea, Y Maslyennikov… - International Journal of …, 2024 - mdpi.com
The mechanism underlying podocyte dysfunction in minimal change disease (MCD)
remains unknown. This study aimed to shed light on the potential pathophysiology of MCD …
remains unknown. This study aimed to shed light on the potential pathophysiology of MCD …
Gestational Age-Related Urinary Peptidome Changes in Preterm and Term Born Infants
M Brasseler, H Mischak, JP Schanstra, JM Michel… - Neonatology, 2024 - karger.com
Introduction: Preterm infants are at risk for a variety of somatic and neurological disorders. In
recent years, biofluid proteomics has emerged as a potential diagnostic tool for biomarker …
recent years, biofluid proteomics has emerged as a potential diagnostic tool for biomarker …
Uniform Manifold Approximation and Projection-based Assessment of Chronic Kidney Disease Aetiologies based on Urinary Peptidomics
Background The impact of artificial intelligence combined with advanced techniques is ever-
increasing in the biomedical field appearing promising, among others, in chronic kidney …
increasing in the biomedical field appearing promising, among others, in chronic kidney …
[PDF][PDF] Collagen-Derived Peptides in CKD: A Link to Fibrosis. Toxins 2022, 14, 10
Collagen is a major component of the extracellular matrix (ECM) and has an imminent role
in fibrosis, in, among others, chronic kidney disease (CKD). Collagen alpha-1 (I)(col1a1) is …
in fibrosis, in, among others, chronic kidney disease (CKD). Collagen alpha-1 (I)(col1a1) is …