Are grid cells used for navigation? On local metrics, subjective spaces, and black holes

G Ginosar, J Aljadeff, L Las, D Derdikman, N Ulanovsky - Neuron, 2023 - cell.com
The symmetric, lattice-like spatial pattern of grid-cell activity is thought to provide a neuronal
global metric for space. This view is compatible with grid cells recorded in empty boxes but …

Cholinergic modulation of spatial learning, memory and navigation

N Solari, B Hangya - European Journal of Neuroscience, 2018 - Wiley Online Library
Spatial learning, including encoding and retrieval of spatial memories as well as holding
spatial information in working memory generally serving navigation under a broad range of …

Differentiation of mild cognitive impairment using an entorhinal cortex-based test of virtual reality navigation

D Howett, A Castegnaro, K Krzywicka, J Hagman… - Brain, 2019 - academic.oup.com
The entorhinal cortex is one of the first regions to exhibit neurodegeneration in Alzheimer's
disease, and as such identification of entorhinal cortex dysfunction may aid detection of the …

A brainstem locomotor circuit drives the activity of speed cells in the medial entorhinal cortex

MM Carvalho, N Tanke, E Kropff, MP Witter, MB Moser… - Cell reports, 2020 - cell.com
Locomotion activates an array of sensory inputs that may help build the self-position map of
the medial entorhinal cortex (MEC). In this map, speed-coding neurons are thought to …

Origin and role of path integration in the cognitive representations of the hippocampus: computational insights into open questions

F Savelli, JJ Knierim - Journal of Experimental Biology, 2019 - journals.biologists.com
Path integration is a straightforward concept with varied connotations that are important to
different disciplines concerned with navigation, such as ethology, cognitive science, robotics …

The medial septum as a potential target for treating brain disorders associated with oscillopathies

Y Takeuchi, AJ Nagy, L Barcsai, Q Li… - Frontiers in Neural …, 2021 - frontiersin.org
The medial septum (MS), as part of the basal forebrain, supports many physiological
functions, from sensorimotor integration to cognition. With often reciprocal connections with …

Spatial learning impairments and discoordination of entorhinal‐hippocampal circuit coding following prolonged febrile seizures

ML Kloc, Y Chen, JM Daglian, GL Holmes… - …, 2023 - Wiley Online Library
How the development and function of neural circuits governing learning and memory are
affected by insults in early life remains poorly understood. The goal of this study was to …

A map of spatial navigation for neuroscience

E Parra-Barrero, S Vijayabaskaran, E Seabrook… - Neuroscience & …, 2023 - Elsevier
Spatial navigation has received much attention from neuroscientists, leading to the
identification of key brain areas and the discovery of numerous spatially selective cells …

Cell type, sub-region, and layer-specific speed representation in the hippocampal–entorhinal circuit

M Iwase, T Kitanishi, K Mizuseki - Scientific Reports, 2020 - nature.com
It has been hypothesised that speed information, encoded by 'speed cells', is important for
updating spatial representation in the hippocampus and entorhinal cortex to reflect ongoing …

Stellate cells in the medial entorhinal cortex are required for spatial learning

SA Tennant, L Fischer, DLF Garden, KZ Gerlei… - Cell reports, 2018 - cell.com
Spatial learning requires estimates of location that may be obtained by path integration or
from positional cues. Grid and other spatial firing patterns of neurons in the superficial …