Cryptococcus neoformans and Cryptococcus gattii species complexes cause
meningoencephalitis with high fatality rates and considerable morbidity, particularly in …

HIV-associated cryptococcal meningitis is by far the most common cause of adult meningitis
in many areas of the world that have high HIV seroprevalence. In most areas in Sub …

Background Cryptococcus is the most common cause of meningitis in adults living with HIV
in sub-Saharan Africa. Global burden estimates are crucial to guide prevention strategies …

Background Fungal diseases range from relatively-minor superficial and mucosal infections
to severe, life-threatening systemic infections. Delayed diagnosis and treatment can lead to …

Cryptococcosis is a major worldwide disseminated invasive fungal infection. Cryptococcosis,
particularly in its most lethal manifestation of cryptococcal meningitis, accounts for …

Hydrocephalus is the most common neurosurgical disorder worldwide and is characterized
by enlargement of the cerebrospinal fluid (CSF)-filled brain ventricles resulting from failed …

Invasive fungal infections (IFIs) are a major cause of HIV-related mortality globally. Despite
widespread rollout of combined antiretroviral therapy, there are still up to 1 million deaths …

Inflammation is emerging as a critical mechanism underlying neurological disorders of
various etiologies, yet its role in altering brain function as a consequence of neuroinfectious …

Cryptococcosis has evolved into a major invasive fungal disease over the last century. Its
primary epidemiology has been focused on three major outbreaks of disease that reflects …

Cryptococcal meningitis causes morbidity and mortality worldwide. The burden of disease is
greatest in middle-and low-income countries with a high incidence of human …