Abstract Background In the United States, Black men are at highest risk for being diagnosed
with and dying from prostate cancer. Given this disparity, we examined relevant data to …

The transferability and clinical value of genetic risk scores (GRSs) across populations
remain limited due to an imbalance in genetic studies across ancestrally diverse …

Background Prostate cancer is the most diagnosed cancer in African American men, yet
prostate cancer screening regimens in this group are poorly guided by existing evidence …

African ancestry is a significant risk factor for prostate cancer and advanced disease. Yet,
genetic studies have largely been conducted outside the context of Sub-Saharan Africa …

Genome-wide association studies (GWAS) have underrepresented individuals from non-
European populations, impeding progress in characterizing the genetic architecture and …

Prostate cancer (PCa) is a significant health burden in Sub-Saharan Africa, with mortality
rates loosely linked to African ancestry. Yet studies aimed at identifying contributing risk …

Abstract Background Prostate cancer (PCa) is a significant health burden for African men,
with mortality rates more than double global averages. The prostate specific Anoctamin 7 …

Prostate-specific membrane antigen (PSMA) is a transmembrane glycoprotein expressed in
the majority of prostate cancer (PCa). PSMA has an enzymatic function that makes metabolic …

Abstract Background African American (AA) men have the highest incidence and mortality
rates of prostate cancer (PCa) among all racial groups in the United States. While race is a …

Purpose: Despite successful clinical management of castration-sensitive prostate cancer
(CSPC), the 5-year survival rate for men with castration-resistant prostate cancer is only …