Keratinases specifically degrade insoluble keratin waste, thus contributing to environmental
protection and sustainable biomass development. However, their industrial application is …

Cold shock adaptability is a key survival skill of gut bacteria of warm-blooded animals.
Escherichia coli cold shock responses are controlled by a complex multi-gene, timely …

Owing to the nondeterministic and nonlinear nature of gene expression, the steady-state
intracellular protein abundance of a clonal population forms a distribution. The …

The topology of the transcription factor network (TFN) of Escherichia coli is far from uniform,
with 22 global regulator (GR) proteins controlling one-third of all genes. So far, their …

Closely spaced promoters are ubiquitous in prokaryotic and eukaryotic genomes. How their
structure and dynamics relate remains unclear, particularly for tandem formations. To study …

The robustness and sensitivity of gene networks to environmental changes is critical for cell
survival. How gene networks produce specific, chronologically ordered responses to …

[目的] 为解决在D-乳酸工业发酵生产中使用农业粗加工或废弃物等廉价原料(含有少量L-乳酸)
而导致终产物D-乳酸光纯降低的问题.[方法] 构建了带有不同启动子的L-乳酸脱氢酶基因lldD …

Gene regulation is essential for life and controlled by regulatory DNA. Mutations can modify
the activity of regulatory DNA, and also create new regulatory DNA, a process called …

Closely spaced promoters are ubiquitous in prokaryotic and eukaryotic genomes. How their
structure and dynamics relate remains unclear, particularly for tandem formations. To study …

In single cells, the process of gene transcription generally demonstrates complicated and
stochastic behaviors. The stochasticity of transcription brings about large variations in the …