Chemical strategies to engineer hydrogels for cell culture
Two-dimensional and three-dimensional cell culture systems are widely used for biological
studies, and are the basis of the organoid, tissue engineering and organ-on-chip research …
studies, and are the basis of the organoid, tissue engineering and organ-on-chip research …
Synthetic alternatives to Matrigel
EA Aisenbrey, WL Murphy - Nature Reviews Materials, 2020 - nature.com
Matrigel, a basement-membrane matrix extracted from Engelbreth–Holm–Swarm mouse
sarcomas, has been used for more than four decades for a myriad of cell-culture …
sarcomas, has been used for more than four decades for a myriad of cell-culture …
Recent advances in hyaluronic acid hydrogels for biomedical applications
CB Highley, GD Prestwich, JA Burdick - Current opinion in biotechnology, 2016 - Elsevier
Highlights•New modifications to hyaluronic acid (HA) enable both covalent crosslinking and
supramolecular assembly.•Composite HA hydrogels permit controlled drug delivery and …
supramolecular assembly.•Composite HA hydrogels permit controlled drug delivery and …
Activated ester containing polymers: opportunities and challenges for the design of functional macromolecules
Rapidly growing demand of functional polymers in various interdisciplinary areas of
research has accentuated the need for modern synthetic tools to develop advanced …
research has accentuated the need for modern synthetic tools to develop advanced …
[HTML][HTML] Challenges and strategies for improving the regenerative effects of mesenchymal stromal cell-based therapies
S Baldari, G Di Rocco, M Piccoli, M Pozzobon… - International journal of …, 2017 - mdpi.com
Cell-based therapies have the potential to revolutionize current treatments for diseases with
high prevalence and related economic and social burden. Unfortunately, clinical trials have …
high prevalence and related economic and social burden. Unfortunately, clinical trials have …
Graphene: A versatile platform for nanotheranostics and tissue engineering
The sustained extensive research on graphene and its derivatives in the last decade
portrayed its significance in the field of material science and carved its own niche in …
portrayed its significance in the field of material science and carved its own niche in …
Tissue engineering strategies for promoting vascularized bone regeneration
S Almubarak, H Nethercott, M Freeberg, C Beaudon… - Bone, 2016 - Elsevier
This review focuses on current tissue engineering strategies for promoting vascularized
bone regeneration. We review the role of angiogenic growth factors in promoting …
bone regeneration. We review the role of angiogenic growth factors in promoting …
Multilayered polycaprolactone/gelatin fiber-hydrogel composite for tendon tissue engineering
Regeneration of injured tendon and ligament (T&L) remains a clinical challenge due to their
poor intrinsic healing capacity. Tissue engineering provides a promising alternative …
poor intrinsic healing capacity. Tissue engineering provides a promising alternative …
Heparin-based and heparin-inspired hydrogels: size-effect, gelation and biomedical applications
Heparin is the highest negatively charged biomolecule, which is a polysaccharide belonging
to the glycosaminoglycan family, and its role as a regulator of various proteins, cells and …
to the glycosaminoglycan family, and its role as a regulator of various proteins, cells and …
[HTML][HTML] Biomaterial-based endochondral bone regeneration: a shift from traditional tissue engineering paradigms to developmentally inspired strategies
There is an urgent, clinical need for an alternative to the use of autologous grafts for the ever
increasing number of bone grafting procedures performed annually. Herein, we describe a …
increasing number of bone grafting procedures performed annually. Herein, we describe a …