The blood coagulation protein fibrinogen is deposited in the brain in a wide range of
neurological diseases and traumatic injuries with blood–brain barrier (BBB) disruption …

Major progress has been made during the past three decades in understanding the
inflammatory process and pathogenetic mechanisms in multiple sclerosis (MS) …

An international group of neurologists and radiologists developed revised guidelines for
standardized brain and spinal cord MR imaging for the diagnosis and follow-up of MS. A …

This book presents 55 clinical cases emphasizing the basic science aspects of pathology
and is “the closest you can get to the wards without seeing patients.” Each case includes an …

Standardization of terminology used to describe the pattern and course of MS is essential for
mutual understanding between clinicians and investigators. It is particularly important in …

Leakage of Gd‐DTPA through a defective blood‐brain barrier is measured quantitatively
using dynamic MRI scanning, in which repeated scans are made after a bolus injection …

Sudden sensorineural hearing loss is usually unilateral and can be associated with tinnitus
and vertigo. In most cases the cause is not identified, although various infective, vascular …

This article provides a comprehensive overview of the pathology of multiple sclerosis (MS),
including recent insights into its molecular neuropathology and immunology. It shows that all …

Lesions and neurologic disability in inflammatory CNS diseases such as multiple sclerosis
(MS) result from the translocation of leukocytes and humoral factors from the vasculature …

Background Previous trials of interferon β in multiple sclerosis (MS) have shown efficacy, but
the degree of clinical benefit remains uncertain, and the optimum dose is not known. We …