Cryptococcosis in the era of AIDS--100 years after the discovery of Cryptococcus neoformans

TG Mitchell, JR Perfect - Clinical microbiology reviews, 1995 - Am Soc Microbiol
Although Cryptococcus neoformans and cryptococcosis have existed for several millennia, a
century has passed since the discovery of this encapsulated yeast and its devastating …

Virulence in Cryptococcus species

H Ma, RC May - Advances in applied microbiology, 2009 - Elsevier
Cryptococcus neoformans and Cryptococcus gattii are the cause of life-threatening
meningoencephalitis in immunocompromised and immunocompetent individuals …

[图书][B] Cryptococcus neoformans

A Casadevall, JR Perfect - 1998 - Citeseer
MATERIALS AND METHODS Strains and media. C. neoformans var. grubii strains H99 (70),
KN99a (55), KN99 (55), KN99aNAT, and KN99NAT were maintained at 80 C. Cultures were …

Cryptococcus neoformans Is a Facultative Intracellular Pathogen in Murine Pulmonary Infection

M Feldmesser, Y Kress, P Novikoff… - Infection and …, 2000 - Am Soc Microbiol
To produce chronic infection, microbial pathogens must escape host immune defenses.
Infection with the human pathogenic fungus Cryptococcus neoformans is typically chronic …

Role of Phagocytosis in the Virulence of Cryptococcus neoformans

M Del Poeta - Eukaryotic cell, 2004 - Am Soc Microbiol
Phagocytosis is a receptor-mediated process that leads to the internalization of foreign
particles into phagocytic cells. Phagocytic cells, such as macrophages, dendritic cells, and …

An innate immune system cell is a major determinant of species-related susceptibility differences to fungal pneumonia

X Shao, A Mednick, M Alvarez… - The journal of …, 2005 - journals.aai.org
Rats and mice are considered resistant and susceptible hosts, respectively, for experimental
cryptococcosis. For both species, alveolar macrophages (AM) are central components of the …

[HTML][HTML] Pulmonary Macrophage and Dendritic Cell Responses to Cryptococcus neoformans

BN Nelson, AN Hawkins, KL Wozniak - Frontiers in cellular and …, 2020 - frontiersin.org
The fungal pathogen Cryptococcus neoformans can cause life-threatening infections in
immune compromised individuals. This pathogen is typically acquired via inhalation, and …

The cryptococcal enzyme inositol phosphosphingolipid-phospholipase C confers resistance to the antifungal effects of macrophages and promotes fungal …

JM Shea, TB Kechichian, C Luberto… - Infection and …, 2006 - Am Soc Microbiol
In recent years, sphingolipids have emerged as critical molecules in the regulation of
microbial pathogenesis. In fungi, the synthesis of complex sphingolipids is important for the …

Killing of Cryptococcus neoformans strains by human neutrophils and monocytes

MF Miller, TG Mitchell - Infection and immunity, 1991 - Am Soc Microbiol
The susceptibility of various strains of Cryptococcus neoformans to killing by human
polymorphonuclear leukocytes (PMNs) and monocytes was investigated. Five previously …

Human alveolar and peritoneal macrophages mediate fungistasis independently of L-arginine oxidation to nitrite or nitrate

ML Cameron, DL Granger, JB Weinberg… - Am Rev Respir …, 1990 - atsjournals.org
Human alveolar macrophages (HAM) from 28 normal volunteers ware found to Inhibit
replication of Cryptococcus neoformans. Conditions under which funglstasls occurred ware …