Biological neutralization represents a general strategy that deploys therapeutic agents to
bind with harmful molecules or infectious pathogens, block their bioactivity, and thus prevent …

Organophosphate (OP)-induced brain damage is defined as progressive damage to the
brain, resulting from the cholinergic neuronal excitotoxicity and dysfunction induced by OP …

Various environmental contaminants including heavy metals, pesticides and antibiotics can
contaminate food and water, leading to adverse effects on human health, such as …

Acetylcholinesterase is the physiological target for acute toxicity of nerve agents. Attempts to
protect acetylcholinesterase from phosphylation by nerve agents, is currently achieved by …

Organophosphate poisoning is highly lethal as organophosphates, which are commonly
found in insecticides and nerve agents, cause irreversible phosphorylation and inactivation …

Organophosphorus agents (OP s) irreversibly inhibit acetylcholinesterase (AC hE) causing a
major cholinergic syndrome. The medical counter‐measures of OP poisoning have not …

Bone mass accrual is a major determinant of skeletal mass, governed by bone remodeling,
which consists of bone resorption by osteoclasts and bone formation by osteoblasts. Bone …

Organophosphorous compounds have been employed as pesticides and chemical warfare
nerve agents. Toxicity of organophosphorous compounds is a result of excessive cholinergic …

Abstract Organophosphorous (OP) Nerve agents (NAs) are known as the deadliest chemical
warfare agents. They are divided into two classes of G and V agents. Most of them are liquid …

Sažetak Phosphylation of the pivotal enzyme acetylcholinesterase (AChE) by nerve agents
(NAs) leads to irreversible inhibition of the enzyme and accumulation of neurotransmitter …