Four billion years of microbial terpenome evolution

Y Hoshino, L Villanueva - FEMS microbiology reviews, 2023 - academic.oup.com
Terpenoids, also known as isoprenoids, are the largest and most diverse class of organic
compounds in nature and are involved in many membrane-associated cellular processes …

The production of diverse brGDGTs by an Acidobacterium providing a physiological basis for paleoclimate proxies

Y Chen, F Zheng, H Yang, W Yang, R Wu, X Liu… - … et Cosmochimica Acta, 2022 - Elsevier
Microbial lipid biomarkers preserved in geological archives can be used to explore past
climate changes. Branched glycerol dialkyl glycerol tetraethers (brGDGTs) are unique …

Discovery, structure and mechanism of a tetraether lipid synthase

CT Lloyd, DF Iwig, B Wang, M Cossu, WW Metcalf… - Nature, 2022 - nature.com
Archaea synthesize isoprenoid-based ether-linked membrane lipids, which enable them to
withstand extreme environmental conditions, such as high temperatures, high salinity, and …

Archaeal lipids

T Řezanka, L Kyselová, DJ Murphy - Progress in Lipid Research, 2023 - Elsevier
The major archaeal membrane glycerolipids are distinguished from those of bacteria and
eukaryotes by the contrasting stereochemistry of their glycerol backbones, and by the use of …

Production of diverse brGDGTs by Acidobacterium Solibacter usitatus in response to temperature, pH, and O2 provides a culturing perspective on brGDGT proxies …

TA Halamka, JH Raberg, JM McFarlin… - …, 2023 - Wiley Online Library
Branched glycerol dialkyl glycerol tetraethers (brGDGTs) are bacterial membrane lipids that
are frequently employed as paleoenvironmental proxies because of the strong empirical …

Identification of two archaeal GDGT lipid–modifying proteins reveals diverse microbes capable of GMGT biosynthesis and modification

AA Garcia, GL Chadwick, XL Liu… - Proceedings of the …, 2024 - National Acad Sciences
Archaea produce unique membrane-spanning lipids (MSLs), termed glycerol dialkyl glycerol
tetraethers (GDGTs), which aid in adaptive responses to various environmental challenges …

[HTML][HTML] The impact of soil chemistry, moisture and temperature on branched and isoprenoid GDGTs in soils: A study using six globally distributed elevation transects

C De Jonge, J Guo, P Hällberg, M Griepentrog… - Organic …, 2024 - Elsevier
Glycerol dialkyl glycerol tetraethers (GDGTs) are microbial membrane-spanning lipids that
are produced in a variety of environments. To better understand the potentially confounding …

Thermophilic archaeon orchestrates temporal expression of GDGT ring synthases in response to temperature and acidity stress

W Yang, H Chen, Y Chen, A Chen… - Environmental …, 2023 - Wiley Online Library
Glycerol dibiphytanyl glycerol tetraethers (GDGTs) are unique archaeal membrane‐
spanning lipids with 0–8 cyclopentane rings on the biphytanyl chains. The cyclization …

Disentangling the lipid divide: Identification of key enzymes for the biosynthesis of membrane-spanning and ether lipids in Bacteria

DX Sahonero-Canavesi, MF Siliakus… - Science …, 2022 - science.org
Bacterial membranes are composed of fatty acids (FAs) ester-linked to glycerol-3-
phosphate, while archaea have membranes made of isoprenoid chains ether-linked to …

Enhanced production of highly methylated brGDGTs linked to anaerobic bacteria from sediments of the Mariana Trench

Z Zeng, W Xiao, F Zheng, Y Chen, Y Zhu… - Frontiers in Marine …, 2023 - frontiersin.org
Branched glycerol dialkyl glycerol tetraethers (brGDGTs) are bacterial membrane lipids that
are widely used in terrestrial paleoclimatic reconstructions. Recent studies have reported …