[HTML][HTML] Contribution of adipose tissue inflammation to the development of type 2 diabetes mellitus

MS Burhans, DK Hagman, JN Kuzma… - Comprehensive …, 2018 - ncbi.nlm.nih.gov
The objective of this comprehensive review is to summarize and discuss the available
evidence of how adipose tissue inflammation affects insulin sensitivity and glucose …

Animal models of metabolic syndrome: a review

SK Wong, KY Chin, FH Suhaimi, A Fairus… - Nutrition & …, 2016 - Springer
Metabolic syndrome (MetS) consists of several medical conditions that collectively predict
the risk for cardiovascular disease better than the sum of individual conditions. The risk of …

Human mesenchymal stem cell derived exosomes alleviate type 2 diabetes mellitus by reversing peripheral insulin resistance and relieving β-cell destruction

Y Sun, H Shi, S Yin, C Ji, X Zhang, B Zhang, P Wu… - ACS …, 2018 - ACS Publications
Exosomes are nanosized extracellular vesicles (EVs) that show great promise in tissue
regeneration and injury repair as mesenchymal stem cell (MSC). MSC has been shown to …

Exercise prevents weight gain and alters the gut microbiota in a mouse model of high fat diet-induced obesity

CC Evans, KJ LePard, JW Kwak, MC Stancukas… - PloS one, 2014 - journals.plos.org
Background Diet-induced obesity (DIO) is a significant health concern which has been
linked to structural and functional changes in the gut microbiota. Exercise (Ex) is effective in …

[HTML][HTML] Promising treatment for type 2 diabetes: fecal microbiota transplantation reverses insulin resistance and impaired islets

H Wang, Y Lu, Y Yan, S Tian, D Zheng… - Frontiers in cellular …, 2020 - frontiersin.org
Type 2 diabetes is a common metabolic disorder related to insulin resistance, or deficiency
of insulin secretion, caused by decreased insulin sensitivity and destruction of islet structure …

Faecal virome transplantation decreases symptoms of type 2 diabetes and obesity in a murine model

TS Rasmussen, CMJ Mentzel, W Kot, JL Castro-Mejía… - Gut, 2020 - gut.bmj.com
Objective Development of obesity and type 2 diabetes (T2D) are associated with gut
microbiota (GM) changes. The gut viral community is predominated by bacteriophages …

Microvesicles and exosomes: new players in metabolic and cardiovascular disease

C Lawson, JM Vicencio, DM Yellon… - Journal of …, 2016 - joe.bioscientifica.com
The past decade has witnessed an exponential increase in the number of publications
referring to extracellular vesicles (EVs). For many years considered to be extracellular …

Prolonged PM2. 5 exposure elevates risk of oxidative stress-driven nonalcoholic fatty liver disease by triggering increase of dyslipidemia

MX Xu, CX Ge, YT Qin, TT Gu, DS Lou, Q Li… - Free Radical Biology …, 2019 - Elsevier
An increasing number of studies have shown that air pollution containing particulate matter
(PM)≤ 2.5 µm (PM2. 5) plays a significant role in the development of metabolic disorder and …

The clinical significance of pancreatic steatosis

MM Smits, EJM Van Geenen - Nature reviews Gastroenterology & …, 2011 - nature.com
More research is now focused on pancreatic steatosis. Multiple definitions, clinical
associations and synonyms for pancreatic steatosis are described in the literature and can …

Infusion of mesenchymal stem cells ameliorates hyperglycemia in type 2 diabetic rats: identification of a novel role in improving insulin sensitivity

Y Si, Y Zhao, H Hao, J Liu, Y Guo, Y Mu, J Shen… - Diabetes, 2012 - Am Diabetes Assoc
Infusion of mesenchymal stem cells (MSCs) has been shown to effectively lower blood
glucose in diabetic individuals, but the mechanism involved could not be adequately …