Xanthine oxidoreductase is involved in macrophage foam cell formation and atherosclerosis development

A Kushiyama, H Okubo, H Sakoda… - … , and vascular biology, 2012 - Am Heart Assoc
Objective—Hyperuricemia is common in patients with metabolic syndrome. We investigated
the role of xanthine oxidoreductase (XOR) in atherosclerosis development, and the effects of …

[HTML][HTML] Empaglifozin mitigates NAFLD in high-fat-fed mice by alleviating insulin resistance, lipogenesis and ER stress

TI Petito-da-Silva, V Souza-Mello… - Molecular and cellular …, 2019 - Elsevier
Aim To evaluate the pleiotropic effects of empagliflozin in the liver through lipogenesis, beta-
oxidation, and endoplasmic reticulum stress pathways. Methods Male C57Bl/6 mice, 3 …

A critical analysis of three quantitative methods of assessment of hepatic steatosis in liver biopsies

M Catta-Preta, LS Mendonca, J Fraulob-Aquino… - Virchows Archiv, 2011 - Springer
The issue of adequately quantitatively evaluating hepatic steatosis is still unresolved.
Therefore, we compared three methods of quantitative assessment. Two groups of mice (n …

Dietary Lycium barbarum Polysaccharide Induces Nrf2/ARE Pathway and Ameliorates Insulin Resistance Induced by High‐Fat via Activation of PI3K/AKT Signaling

Y Yang, W Li, Y Li, Q Wang, L Gao… - Oxidative medicine and …, 2014 - Wiley Online Library
Lycium barbarum polysaccharide (LBP), an antioxidant from wolfberry, displays the
antioxidative and anti‐inflammatory effects on experimental models of insulin resistance in …

Carnosic acid as a major bioactive component in rosemary extract ameliorates high-fat-diet-induced obesity and metabolic syndrome in mice

Y Zhao, R Sedighi, P Wang, H Chen… - Journal of agricultural …, 2015 - ACS Publications
In this study, we investigated the preventive effects of carnosic acid (CA) as a major
bioactive component in rosemary extract (RE) on high-fat-diet-induced obesity and …

Fatty pancreas-centered metabolic basis of pancreatic adenocarcinoma: From obesity, diabetes and pancreatitis to oncogenesis

ML Chang - Biomedicines, 2022 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest types of cancer, and it is
currently the third most common cause of cancer death in the USA Progress in the fight …

Effects of type II diabetes mellitus on tendon homeostasis and healing

AEC Nichols, I Oh, AE Loiselle - Journal of Orthopaedic …, 2020 - Wiley Online Library
Over 300,000 tendon repairs are performed annually in the United States to repair damage
to tendons as a result of either acute trauma or chronic tendinopathy. Individuals with type II …

Odd-numbered agaro-oligosaccharides alleviate type 2 diabetes mellitus and related colonic microbiota dysbiosis in mice

X Wang, Z Yang, X Xu, H Jiang, C Cai, G Yu - Carbohydrate polymers, 2020 - Elsevier
Agaro-and neoagaro-oligosaccharides with even-numbered sugar units possess a variety of
biological activities. However, the effects of the odd-numbered oligosaccharides from …

Predictors of ectopic fat accumulation in liver and pancreas in obese men and women

AP Rossi, F Fantin, GA Zamboni, G Mazzali… - …, 2011 - Wiley Online Library
The aim of the present study was to determine the relationship between body fat distribution,
adipocytokines, inflammatory markers, fat intake and ectopic fat content of liver and …

[HTML][HTML] Beneficial effects of intermittent fasting on steatosis and inflammation of the liver in mice fed a high-fat or a high-fructose diet

T de Souza Marinho, F Ornellas, S Barbosa-da-Silva… - Nutrition, 2019 - Elsevier
Objective Intermittent fasting (IF) is a nutritional intervention with significant metabolic effects
on the liver that are not yet fully understood. The aim of this study was to investigate the …