The clinical implications of fatty pancreas: a concise review

T Khoury, AW Asombang, TM Berzin, J Cohen… - Digestive diseases and …, 2017 - Springer
Fatty pancreas is a newly recognized condition which is poorly investigated until today as
compared to nonalcoholic fatty liver disease. It is characterized by pancreatic fat …

Multi-technique comparison of atherogenic and MCD NASH models highlights changes in sphingolipid metabolism

SA Montandon, E Somm, U Loizides-Mangold… - Scientific reports, 2019 - nature.com
Lipotoxicity is a key player in the pathogenesis of nonalcoholic steatohepatitis (NASH), a
progressive subtype of nonalcoholic fatty liver disease (NAFLD). In the present study, we …

Biological investigations on therapeutic effect of chitosan encapsulated nano resveratrol against gestational diabetes mellitus rats induced by streptozotocin

S Du, Y Lv, N Li, X Huang, X Liu, H Li, C Wang… - Drug delivery, 2020 - Taylor & Francis
The chitosan encapsulation with bioactive compounds (resveratrol) is a significant method
that can be used to raise the stability and effectiveness of substances in gestational diabetes …

Pancreatic fat accumulation, fibrosis, and acinar cell injury in the Zucker diabetic fatty rat fed a chronic high-fat diet

A Matsuda, N Makino, T Tozawa, N Shirahata… - Pancreas, 2014 - journals.lww.com
Objective The histological alteration of the exocrine pancreas in obesity has not been
clarified. In the present study, we investigated biochemical and histological changes in the …

[HTML][HTML] Sodium butyrate arrests pancreato-hepatic synchronous uric acid and lipid dysmetabolism in high fat diet fed Wistar rats

OA Adeyanju, OC Badejogbin, DE Areola… - Biomedicine & …, 2021 - Elsevier
High fat diet (HFD) is a risk factor for metabolic syndrome which is characterized by overt
glucose dysmetabolism and tissue derangement. The liver and pancreas are important …

Obesity is associated with changes in oxysterol metabolism and levels in mice liver, hypothalamus, adipose tissue and plasma

O Guillemot-Legris, V Mutemberezi, PD Cani… - Scientific Reports, 2016 - nature.com
Oxysterols are bioactive lipids derived from cholesterol that are linked to inflammatory
processes. Because obesity and metabolic syndrome are characterized by inflammation and …

miR-379 mediates insulin resistance and obesity through impaired angiogenesis and adipogenesis regulated by ER stress

M Abdollahi, M Kato, L Lanting, R Tunduguru… - … Therapy-Nucleic Acids, 2022 - cell.com
We investigated the role of microRNA (miR-379) in the pathogenesis of obesity, adipose
tissue dysfunction, and insulin resistance (IR). We used miR-379 knockout (miR-379KO) …

Oxidative Stress Profile of Mothers and Their Offspring after Maternal Consumption of High‐Fat Diet in Rodents: A Systematic Review and Meta‐Analysis

RQ Moraes-Souza, G Vesentini… - Oxidative medicine …, 2021 - Wiley Online Library
Maternal exposure to the high‐fat diet (HFD) during gestation or lactation can be harmful to
both a mother and offspring. The aim of this systematic review was to identify and evaluate …

Canagliflozin prevents lipid accumulation, mitochondrial dysfunction, and gut microbiota dysbiosis in mice with diabetic cardiovascular disease

X Wang, Z Wang, D Liu, H Jiang, C Cai, G Li… - Frontiers in …, 2022 - frontiersin.org
Type 2 diabetes mellitus (T2DM) is associated with cardiovascular disease (CVD) and
sodium glucose cotransporter 2 inhibitors, as oral medications for T2DM treatment have …

Pancreatic steatosis and metabolic pancreatic disease: a new entity?

F Caldart, N de Pretis, C Luchini, R Ciccocioppo… - Internal and Emergency …, 2023 - Springer
Overweight and obesity are some of the most important health challenges. Many diseases
are related to these metabolic disorders, and, among them, the pancreatic fat accumulation …