Zebrafish as an emerging model for studying complex brain disorders
AV Kalueff, AM Stewart, R Gerlai - Trends in pharmacological sciences, 2014 - cell.com
The zebrafish (Danio rerio) is rapidly becoming a popular model organism in
pharmacogenetics and neuropharmacology. Both larval and adult zebrafish are currently …
pharmacogenetics and neuropharmacology. Both larval and adult zebrafish are currently …
The developing utility of zebrafish models of neurological and neuropsychiatric disorders: A critical review
BD Fontana, NJ Mezzomo, AV Kalueff… - Experimental …, 2018 - Elsevier
Zebrafish (Danio rerio) have become a powerful tool in neuroscience research due to their
genetic tractability, molecular/physiological conservation, small body size, ease of …
genetic tractability, molecular/physiological conservation, small body size, ease of …
Zebrafish: an emerging real-time model system to study Alzheimer's disease and neurospecific drug discovery
S Saleem, RR Kannan - Cell death discovery, 2018 - nature.com
Zebrafish (Danio rerio) is emerging as an increasingly successful model for translational
research on human neurological disorders. In this review, we appraise the high degree of …
research on human neurological disorders. In this review, we appraise the high degree of …
Comparative analyses of zebrafish anxiety-like behavior using conflict-based novelty tests
Modeling of stress and anxiety in adult zebrafish (Danio rerio) is increasingly utilized in
neuroscience research and central nervous system (CNS) drug discovery. Representing the …
neuroscience research and central nervous system (CNS) drug discovery. Representing the …
Zebrafish models in neuropsychopharmacology and CNS drug discovery
Despite the high prevalence of neuropsychiatric disorders, their aetiology and molecular
mechanisms remain poorly understood. The zebrafish (Danio rerio) is increasingly utilized …
mechanisms remain poorly understood. The zebrafish (Danio rerio) is increasingly utilized …
Zebrafish as potential model for developmental neurotoxicity testing: a mini review
The zebrafish is a powerful toxicity model; biochemical assays can be combined with
observations at a structural and functional level within one individual. This mini review …
observations at a structural and functional level within one individual. This mini review …
The zebrafish (Danio rerio) anxiety test battery: comparison of behavioral responses in the novel tank diving and light–dark tasks following exposure to anxiogenic …
BD Fontana, N Alnassar, MO Parker - Psychopharmacology, 2022 - Springer
Rationale Triangulation of approaches (ie, using several tests of the same construct) can be
extremely useful for increasing the robustness of the findings being widely used when …
extremely useful for increasing the robustness of the findings being widely used when …
Examining behavioural test sensitivity and locomotor proxies of anxiety-like behaviour in zebrafish
A Johnson, E Loh, R Verbitsky, J Slessor… - Scientific Reports, 2023 - nature.com
This study assessed the sensitivity of four anxiety-like behaviour paradigms in zebrafish: the
novel tank dive test, shoaling test, light/dark test, and the less common shoal with novel …
novel tank dive test, shoaling test, light/dark test, and the less common shoal with novel …
Seizures induced by pentylenetetrazole in the adult zebrafish: a detailed behavioral characterization
BHM Mussulini, CE Leite, KC Zenki, L Moro, S Baggio… - PloS one, 2013 - journals.plos.org
Pentylenetetrazole (PTZ) is a common convulsant agent used in animal models to
investigate the mechanisms of seizures. Although adult zebrafish have been recently used …
investigate the mechanisms of seizures. Although adult zebrafish have been recently used …
Female adult zebrafish (Danio rerio) show higher levels of anxiety‐like behavior than males, but do not differ in learning and memory capacity
BD Fontana, M Cleal, MO Parker - European Journal of …, 2020 - Wiley Online Library
Zebrafish (Danio rerio) are widely used as a translational model for human neuropsychiatric
conditions. Many studies have not considered sex differences in their analyses. Here, we …
conditions. Many studies have not considered sex differences in their analyses. Here, we …