[HTML][HTML] Biomarkers in atopic dermatitis—a review on behalf of the International Eczema Council
Y Renert-Yuval, JP Thyssen, R Bissonnette… - Journal of Allergy and …, 2021 - Elsevier
Atopic dermatitis (AD) is a common yet complex skin disease, posing a therapeutic
challenge with increasingly recognized different phenotypes among variable patient …
challenge with increasingly recognized different phenotypes among variable patient …
Subtypes of atopic dermatitis: From phenotype to endotype
Y Tokura, S Hayano - Allergology International, 2022 - jstage.jst.go.jp
abstract Atopic dermatitis (AD) is a heterogenous disorder and can be classified into
different types. Stratification of subtypes may enable personalized medicine approaches. AD …
different types. Stratification of subtypes may enable personalized medicine approaches. AD …
Tralokinumab for moderate‐to‐severe atopic dermatitis: results from two 52‐week, randomized, double‐blind, multicentre, placebo‐controlled phase III trials (ECZTRA …
A Wollenberg, A Blauvelt… - British Journal of …, 2021 - academic.oup.com
Background Tralokinumab, a fully human monoclonal antibody, specifically neutralizes
interleukin‐13, a key cytokine driving peripheral inflammation in atopic dermatitis (AD). In …
interleukin‐13, a key cytokine driving peripheral inflammation in atopic dermatitis (AD). In …
Single-cell transcriptome analysis of human skin identifies novel fibroblast subpopulation and enrichment of immune subsets in atopic dermatitis
H He, H Suryawanshi, P Morozov… - Journal of Allergy and …, 2020 - Elsevier
Background Atopic dermatitis (AD) is a prevalent inflammatory skin disease with a complex
pathogenesis involving immune cell and epidermal abnormalities. Despite whole tissue …
pathogenesis involving immune cell and epidermal abnormalities. Despite whole tissue …
Atopic dermatitis endotypes and implications for targeted therapeutics
T Czarnowicki, H He, JG Krueger… - Journal of Allergy and …, 2019 - Elsevier
Recent research advancements indicate that atopic dermatitis (AD) is a complex disease
characterized by different subtypes/phenotypes based on age, disease chronicity, ethnicity …
characterized by different subtypes/phenotypes based on age, disease chronicity, ethnicity …
Type 2 chronic inflammatory diseases: targets, therapies and unmet needs
Over the past two decades, significant progress in understanding of the pathogenesis of type
2 chronic inflammatory diseases has enabled the identification of compounds for more than …
2 chronic inflammatory diseases has enabled the identification of compounds for more than …
Tape strips detect distinct immune and barrier profiles in atopic dermatitis and psoriasis
H He, R Bissonnette, J Wu, A Diaz, ESC Proulx… - Journal of Allergy and …, 2021 - Elsevier
Background Our current understanding of atopic dermatitis (AD) and psoriasis
pathophysiology is largely derived from skin biopsy studies that cause scarring and may be …
pathophysiology is largely derived from skin biopsy studies that cause scarring and may be …
[HTML][HTML] Delgocitinib ointment, a topical Janus kinase inhibitor, in adult patients with moderate to severe atopic dermatitis: A phase 3, randomized, double-blind …
H Nakagawa, O Nemoto, A Igarashi, H Saeki… - Journal of the American …, 2020 - Elsevier
Background Previous studies showed the potential effectiveness of delgocitinib ointment, a
novel topical Janus kinase inhibitor, in atopic dermatitis (AD). Objective This study aimed to …
novel topical Janus kinase inhibitor, in atopic dermatitis (AD). Objective This study aimed to …
Baricitinib in patients with moderate-to-severe atopic dermatitis: results from a randomized monotherapy phase 3 trial in the United States and Canada (BREEZE-AD5)
EL Simpson, S Forman, JI Silverberg, M Zirwas… - Journal of the American …, 2021 - Elsevier
Background Baricitinib, an oral selective Janus kinase 1/Janus kinase 2 inhibitor, is being
studied for moderate-to-severe atopic dermatitis (AD) in adults. Objective To evaluate the …
studied for moderate-to-severe atopic dermatitis (AD) in adults. Objective To evaluate the …
Biologics for treatment of atopic dermatitis: current status and future prospect
T Ratchataswan, TM Banzon, JP Thyssen… - The Journal of Allergy …, 2021 - Elsevier
Atopic dermatitis (AD) is a common inflammatory skin disease characterized by intense
pruritus and recurrent eczematous lesions that significantly impair quality of life. It is a …
pruritus and recurrent eczematous lesions that significantly impair quality of life. It is a …