Clostridium difficile ribotype 017 – characterization, evolution and epidemiology of the dominant strain in Asia

K Imwattana, DR Knight, B Kullin… - Emerging Microbes & …, 2019 - Taylor & Francis
Clostridium difficile ribotype (RT) 017 is an important toxigenic C. difficile RT which, due to a
deletion in the repetitive region of the tcdA gene, only produces functional toxin B. Strains …

Antimicrobial resistance in Clostridium difficile ribotype 017

K Imwattana, DR Knight, B Kullin… - Expert review of anti …, 2020 - Taylor & Francis
Introduction: Antimicrobial resistance (AMR) played an important role in the initial outbreaks
of Clostridium difficile infection (CDI) in the 1970s. C. difficile ribotype (RT) 017 has emerged …

Clostridioides difficile epidemiology in the Middle and the Far East

M Brajerova, J Zikova, M Krutova - Anaerobe, 2022 - Elsevier
Objectives Clostridioides difficile is an important pathogen of healthcare-associated
gastrointestinal infections. Recently, an increased number of C. difficile infection (CDI) …

Laboratory-based surveillance of Clostridium difficile infection in Australian health care and community settings, 2013 to 2018

S Hong, P Putsathit, N George, C Hemphill… - Journal of Clinical …, 2020 - Am Soc Microbiol
In the early 2000s, a binary toxin (CDT)-producing strain of Clostridium difficile, ribotype 027
(RT027), caused extensive outbreaks of diarrheal disease in North America and Europe …

Genomic basis of antimicrobial resistance in non-toxigenic Clostridium difficile in Southeast Asia

K Imwattana, P Kiratisin, TV Riley, DR Knight - Anaerobe, 2020 - Elsevier
Despite being incapable of causing Clostridium difficile infection, non-toxigenic C. difficile
(NTCD) may still be relevant. This study explored the role of NTCD as a reservoir of …

[HTML][HTML] Ribotype Classification of Clostridioides difficile Isolates Is Not Predictive of the Amino Acid Sequence Diversity of the Toxin Virulence Factors TcdA and TcdB

Z Li, K Lee, U Rajyaguru, CH Jones, S Janezic… - Frontiers in …, 2020 - frontiersin.org
Clostridioides (Clostridium) difficile is the most commonly recognized cause of infectious
diarrhea in healthcare settings. Currently there is no vaccine to prevent initial or recurrent C …

Global evolutionary dynamics and resistome analysis of Clostridioides difficile ribotype 017

K Imwattana, P Putsathit, DA Collins… - Microbial …, 2022 - microbiologyresearch.org
Clostridioides difficile PCR ribotype (RT) 017 ranks among the most successful strains of C.
difficile in the world. In the past three decades, it has caused outbreaks on four continents …

Molecular Characterization of, and Antimicrobial Resistance in, Clostridioides difficile from Thailand, 2017–2018

K Imwattana, P Putsathit, DR Knight… - Microbial Drug …, 2021 - liebertpub.com
Antimicrobial resistance (AMR) plays an important role in the pathogenesis and spread of
Clostridioides difficile infection (CDI). Many antimicrobials, such as fluoroquinolones, have …

The burden of Clostridioides difficile infections in South-East Asia and the Western Pacific: A narrative review

FJ Angulo, C Ghia, MA Fletcher, E Ozbilgili, G Morales - Anaerobe, 2024 - Elsevier
Abstract Background Clostridioides difficile (formerly Clostridium difficile) is well-
documented in Europe and North America to be a common cause of healthcare-associated …

Environmental contamination with Clostridioides (Clostridium) difficile in Vietnam

PA Khun, LD Phi, HTT Bui, NT Bui… - Journal of applied …, 2023 - academic.oup.com
Aims To investigate the prevalence, molecular type, and antimicrobial susceptibility of
Clostridioides difficile in the environment in Vietnam, where little is known about C. difficile …