Structural insights into nuclear transcription by eukaryotic DNA-dependent RNA polymerases
The eukaryotic transcription apparatus synthesizes a staggering diversity of RNA molecules.
The labour of nuclear gene transcription is, therefore, divided among multiple DNA …
The labour of nuclear gene transcription is, therefore, divided among multiple DNA …
Causes and consequences of RNA polymerase II stalling during transcript elongation
M Noe Gonzalez, D Blears, JQ Svejstrup - Nature reviews Molecular …, 2021 - nature.com
The journey of RNA polymerase II (Pol II) as it transcribes a gene is anything but a smooth
ride. Transcript elongation is discontinuous and can be perturbed by intrinsic regulatory …
ride. Transcript elongation is discontinuous and can be perturbed by intrinsic regulatory …
Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase ρ
N Said, T Hilal, ND Sunday, A Khatri, J Bürger, T Mielke… - Science, 2021 - science.org
INTRODUCTION Factor-dependent transcription termination is essential to limit pervasive
transcription, maintain genome stability, balance the expression of neighboring genes, and …
transcription, maintain genome stability, balance the expression of neighboring genes, and …
[HTML][HTML] The Mediator kinase module: an interface between cell signaling and transcription
O Luyties, DJ Taatjes - Trends in biochemical sciences, 2022 - cell.com
The Mediator complex controls RNA polymerase II (pol II) activity by coordinating the
assembly of pol II regulatory factors at transcription start sites and by mediating interactions …
assembly of pol II regulatory factors at transcription start sites and by mediating interactions …
[PDF][PDF] DNA-directed termination of RNA polymerase II transcription
Summary RNA polymerase II (RNAPII) transcription involves initiation from a promoter,
transcriptional elongation through the gene, and termination in the terminator region. In …
transcriptional elongation through the gene, and termination in the terminator region. In …
An integrated model for termination of RNA polymerase III transcription
RNA polymerase III (RNAPIII) synthesizes essential and abundant noncoding RNAs such as
transfer RNAs. Controlling RNAPIII span of activity by accurate and efficient termination is a …
transfer RNAs. Controlling RNAPIII span of activity by accurate and efficient termination is a …
Pervasive transcription: a controlled risk
T Villa, O Porrua - The FEBS Journal, 2023 - Wiley Online Library
Transcriptome‐wide interrogation of eukaryotic genomes has unveiled the pervasive nature
of RNA polymerase II transcription. Virtually, any DNA region with an accessible chromatin …
of RNA polymerase II transcription. Virtually, any DNA region with an accessible chromatin …
Mechanisms of eukaryotic transcription termination at a glance
Transcription termination is the final step of a transcription cycle, which induces the release
of the transcript at the termination site and allows the recycling of the polymerase for the next …
of the transcript at the termination site and allows the recycling of the polymerase for the next …
Transcription by RNA polymerase II and the CTD-chromatin crosstalk
The epigenetic phenomenon is known to derive the phenotypic variation of an organism
through an interconnected cellular network of histone modifications, DNA methylation and …
through an interconnected cellular network of histone modifications, DNA methylation and …
Single-molecule characterization of Sen1 translocation properties provides insights into eukaryotic factor-dependent transcription termination
Sen1 is an essential helicase for factor-dependent transcription termination in
Saccharomyces cerevisiae, whose molecular-motor mechanism has not been well …
Saccharomyces cerevisiae, whose molecular-motor mechanism has not been well …