Numerous mitochondrial constituents and metabolic products can function as damage-
associated molecular patterns (DAMPs) and promote inflammation when released into the …

Background Cancer is the most prevalent cause of death globally, and radiotherapy is
considered the standard of care for most solid tumors, including lung, breast, esophageal …

The BCL-2 family protein BAX is a major regulator of physiological and pathological cell
death. BAX predominantly resides in the cytosol in a quiescent state and upon stress, it …

Mitochondria are cellular organelles with a major role in many cellular processes, including
not only energy production, metabolism, and calcium homeostasis but also regulated cell …

Tumor-positive resection margins after surgery can result in tumor recurrence and
metastasis. Although adjuvant postoperative radiotherapy and chemotherapy have been …

Herein, an ultrasensitive and versatile electrochemical biosensor was developed through
the target-controlled capture and release of signal probe-loaded DNA nanotube for the …

Ferroptosis has recently become an attractive strategy to combat the chemoresistance of
cancer cells, but the intracellular ferroptosis defense system greatly challenges the efficient …

Abnormal cellular apoptosis plays a pivotal role in the pathogenesis of Multiple Myeloma
(MM). Over the years, BCL-2, a crucial anti-apoptotic protein, has garnered significant …

Obesity is a major risk factor for cancer. Conventional thought suggests that elevated
adiposity predisposes to heightened inflammatory stress and potentiates tumor growth, yet …

Cancer has a considerably higher fatality rate than other diseases globally and is one of the
most lethal and profoundly disruptive ailments. The increasing incidence of cancer among …