COVID-19, myocarditis and pericarditis

DL Fairweather, DJ Beetler, DN Di Florio… - Circulation …, 2023 - Am Heart Assoc
Viral infections are a leading cause of myocarditis and pericarditis worldwide, conditions that
frequently coexist. Myocarditis and pericarditis were some of the early comorbidities …

Entry and exit of extracellular vesicles to and from the blood circulation

D Iannotta, AW Kijas, AE Rowan, J Wolfram - Nature Nanotechnology, 2024 - nature.com
Extracellular vesicles (EVs) are biological nanoparticles that promote intercellular
communication by delivering bioactive cargo over short and long distances. Short-distance …

Sex and gender differences in myocarditis and dilated cardiomyopathy: an update

DL Fairweather, DJ Beetler, N Musigk… - Frontiers in …, 2023 - frontiersin.org
In the past decade there has been a growing interest in understanding sex and gender
differences in myocarditis and dilated cardiomyopathy (DCM), and the purpose of this review …

Clinical translation of extracellular vesicles

A Ghodasara, A Raza, J Wolfram… - Advanced …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) occur in a variety of bodily fluids and have gained recent
attraction as natural materials due to their bioactive surfaces, internal cargo, and role in …

Vasculature organotropism in drug delivery

A Amruta, D Iannotta, SW Cheetham, T Lammers… - Advanced Drug Delivery …, 2023 - Elsevier
Over the past decades, there has been an exponential increase in the development of
preclinical and clinical nanodelivery systems, and recently, an accelerating demand to …

Unraveling multilayered extracellular vesicles: Speculation on cause

K Broad, SA Walker, I Davidovich… - Journal of …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are cell‐released, heterogenous nanoparticles that play
important roles in (patho) physiological processes through intercellular communication. EVs …

Extracellular vesicle and lipoprotein interactions

RE Ghebosu, J Pendiuk Goncalves, J Wolfram - Nano Letters, 2023 - ACS Publications
Extracellular vesicles and lipoproteins are lipid-based biological nanoparticles that play
important roles in (patho) physiology. Recent evidence suggests that extracellular vesicles …

Hyaluronic acid: An overlooked extracellular vesicle contaminant

JP Goncalves, RE Ghebosu, XNS Tan… - Journal of …, 2023 - Wiley Online Library
The variable presence of contaminants in extracellular vesicle (EV) samples is one of the
major contributors to a lack of inter‐study reproducibility in the field. Well‐known …

Identification of CD38, CD97, and CD278 on the HIV surface using a novel flow virometry screening assay

J Burnie, C Fernandes, D Chaphekar, D Wei… - Scientific Reports, 2023 - nature.com
While numerous cellular proteins in the HIV envelope are known to alter virus infection,
methodology to rapidly phenotype the virion surface in a high throughput, single virion …

Reconstituted extracellular vesicles from human platelets decrease viral myocarditis in mice

DJ Beetler, KA Bruno, MM Watkins, V Xu, I Chekuri… - Small, 2023 - Wiley Online Library
Patients with viral myocarditis are at risk of sudden death and may progress to dilated
cardiomyopathy (DCM). Currently, no disease‐specific therapies exist to treat viral …