Implications of the changing epidemiology of inflammatory bowel disease in a changing world

M Agrawal, T Jess - United European gastroenterology journal, 2022 - Wiley Online Library
The epidemiology of inflammatory bowel disease (IBD) has undergone considerable shifts
since its emergence in the Western world over a century ago, especially in the last few …

Tumor necrosis factor inhibitors for inflammatory bowel disease

OH Nielsen, MA Ainsworth - New England Journal of Medicine, 2013 - Mass Medical Soc
Tumor Necrosis Factor Inhibitors for Inflammatory Bowel Disease | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

Breaking through the therapeutic ceiling: what will it take?

T Raine, S Danese - Gastroenterology, 2022 - Elsevier
Outcomes for patients starting a new treatment for inflammatory bowel disease are
characterized by uncertainty of treatment response. Although it is natural to hope that new …

Novel trends with biologics in inflammatory bowel disease: sequential and combined approaches

G Privitera, D Pugliese, LR Lopetuso… - Therapeutic …, 2021 - journals.sagepub.com
Inflammatory bowel disease (IBD) management has changed dramatically over the past 20
years, after the introduction of targeted biological therapies. However, the impact of these …

Early biologic treatment decreases risk of surgery in Crohn's disease but not in ulcerative colitis: systematic review and meta-analysis

CCY Law, B Tkachuk, S Lieto, N Narula… - Inflammatory bowel …, 2024 - academic.oup.com
Abstract Background and Aims Inflammatory bowel disease (IBD) can lead to long-term
complications that significantly impact patients' quality of life and healthcare resource …

5‐aminosalicylate maintenance is not superior to no maintenance in patients with newly diagnosed Crohn's disease—A nationwide cohort study

O Atia, I Goren, TS Fischler… - Alimentary …, 2023 - Wiley Online Library
Summary Background 5‐aminosalicylates (5‐ASA) are widely used in Crohn's disease (CD)
despite guidelines advising otherwise. We aimed to assess in nationwide study the …

Tumour necrosis factor inhibitors in inflammatory bowel disease: the story continues

L Peyrin-Biroulet, WJ Sandborn… - Therapeutic …, 2021 - journals.sagepub.com
In the 1990s, tumour necrosis factor-α inhibitor therapy ushered in the biologic therapy era
for inflammatory bowel disease, leading to marked improvements in treatment options and …

[HTML][HTML] Role of the combination of biologics and/or small molecules in the treatment of patients with inflammatory bowel disease

D Balderramo - World Journal of Gastroenterology, 2022 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) is a group of chronic diseases that includes ulcerative
colitis, Crohn's disease, and indeterminate colitis. Patients with IBD require prolonged …

Early intervention in ulcerative colitis: ready for prime time?

V Solitano, F D'Amico, E Zacharopoulou… - Journal of Clinical …, 2020 - mdpi.com
Growing evidence shows that ulcerative colitis (UC) is a progressive disease similar to
Crohn's disease (CD). The UC-related burden is often underestimated by physicians and a …

[HTML][HTML] Innovative pharmaceutical techniques for Paediatric dosage forms: a systematic review on 3D printing, prilling/vibration and microfluidic platform

GF Racaniello, T Silvestri, M Pistone, V D'Amico… - Journal of …, 2024 - Elsevier
The production of paediatric pharmaceutical forms represents a unique challenge within the
pharmaceutical industry. The primary goal of these formulations is to ensure therapeutic …