[HTML][HTML] Drug resistance in liver flukes

I Fairweather, GP Brennan, REB Hanna… - International Journal for …, 2020 - Elsevier
Liver flukes include Fasciola hepatica, Fasciola gigantica, Clonorchis sinensis, Opisthorchis
spp., Fascioloides magna, Gigantocotyle explanatum and Dicrocoelium spp. The two main …

[HTML][HTML] The role of natural products in drug discovery and development against neglected tropical diseases

PM Cheuka, G Mayoka, P Mutai, K Chibale - Molecules, 2016 - mdpi.com
Endemic in 149 tropical and subtropical countries, neglected tropical diseases (NTDs) affect
more than 1 billion people annually, including 875 million children in developing …

[HTML][HTML] Medicinal plants as an alternative to control poultry parasitic diseases

M Jamil, MT Aleem, A Shaukat, A Khan, M Mohsin… - Life, 2022 - mdpi.com
Parasitic infections are a major public health concern affecting millions of people universally.
This review elaborates on the potential impacts of plants and their bioactive components that …

[HTML][HTML] Antimicrobial potential of carvacrol against uropathogenic Escherichia coli via membrane disruption, depolarization, and reactive oxygen species generation

I Khan, A Bahuguna, P Kumar, VK Bajpai… - Frontiers in …, 2017 - frontiersin.org
Bacterial resistance to antibiotics poses a serious threat to cure diseases associated with
microbial infection. Among the resistant bacteria, extended-spectrum β-lactamase (ESBL) …

[HTML][HTML] An appraisal of natural products active against parasitic nematodes of animals

JF Garcia-Bustos, BE Sleebs, RB Gasser - Parasites & Vectors, 2019 - Springer
Here, the scientific and patent literature on the activities of purified natural compounds has
been reviewed, with the aim of assessing their suitability as anthelmintic drug discovery …

Management of osteoarthritis with avocado/soybean unsaponifiables

BA Christiansen, S Bhatti, R Goudarzi, S Emami - Cartilage, 2015 - journals.sagepub.com
Osteoarthritis (OA) is a painful and life-altering disease that severely limits the daily activities
of millions of Americans, and it is one of the most common causes of disability in the world …

[HTML][HTML] Antioxidant and antimicrobial study of Schefflera vinosa leaves crude extracts against rice pathogens

N Singh, A Mansoori, G Jiwani, AU Solanke… - Arabian Journal of …, 2021 - Elsevier
Plant extracts are one of the best possible sources of bioactive molecules, and are being
used globally as an antioxidants and natural antimicrobial compounds. In current study …

Synthesis of quinones with highlighted biological applications: A critical update on the strategies towards bioactive compounds with emphasis on lapachones

EN da Silva Júnior, GAM Jardim, C Jacob… - European Journal of …, 2019 - Elsevier
Naphthoquinones are of key importance in organic synthesis and medicinal chemistry. In the
last few years, various synthetic routes have been developed to prepare bioactive …

[HTML][HTML] Natural products as leads in schistosome drug discovery

BJ Neves, CH Andrade, PVL Cravo - Molecules, 2015 - mdpi.com
Schistosomiasis is a neglected parasitic tropical disease that claims around 200,000 human
lives every year. Praziquantel (PZQ), the only drug recommended by the World Health …

[HTML][HTML] Natural Products That Target the Arginase in Leishmania Parasites Hold Therapeutic Promise

NS Carter, BD Stamper, F Elbarbry, V Nguyen, S Lopez… - Microorganisms, 2021 - mdpi.com
Parasites of the genus Leishmania cause a variety of devastating and often fatal diseases in
humans worldwide. Because a vaccine is not available and the currently small number of …