Darovasertib, a novel treatment for metastatic uveal melanoma

L Cao, S Chen, R Sun, CR Ashby Jr, L Wei… - Frontiers in …, 2023 - frontiersin.org
The FDA granted orphan drug designation to darovasertib, a first-in-class oral, small
molecular inhibitor of protein kinase C (PKC), for the treatment of uveal melanoma, on 2 May …

Adenosine mediates the amelioration of social novelty deficits during rhythmic light treatment of 16p11. 2 deletion female mice

J Ju, X Li, Y Pan, J Du, X Yang, S Men, B Liu… - Molecular …, 2024 - nature.com
Non-invasive brain stimulation therapy for autism spectrum disorder (ASD) has shown
beneficial effects. Recently, we and others demonstrated that visual sensory stimulation …

Selenium supplementation provides potent neuroprotection following cerebral ischemia in mice

Z Zhuo, H Wang, S Zhang, PF Bartlett… - Journal of Cerebral …, 2023 - journals.sagepub.com
Despite progress in reperfusion therapy, functional recovery remains suboptimal in many
stroke patients, with oxidative stress, inflammation, dysbiosis, and secondary …

The chronic effects of a single low-intensity blast exposure on Phosphoproteome networks and cognitive function influenced by mutant tau overexpression

M Jackson, S Chen, TT Nguyen, HR Siedhoff… - International Journal of …, 2024 - mdpi.com
Blast-induced neurotrauma (BINT) is a pressing concern for veterans and civilians exposed
to explosive devices. Affected personnel may have increased risk for long-term cognitive …

Yueju volatile oil plays an integral role in the antidepressant effect by up-regulating ERK/AKT-mediated GLT-1 expression to clear glutamate

B Zhang, D Su, Y Song, H Li, C Chen, L Liao, H Zhang… - Fitoterapia, 2023 - Elsevier
Phytochemical investigation of the volatile oil of Yueju (YJVO) and its constituent herbs
induced the detection of 52 compounds in YJVO, mainly monoterpenes and sesquiterpenes …

Adenosine mediates the amelioration of social novelty deficits during rhythmic light treatment of 16p11. 2+/-female mice

ST Hou, J Ju, X Li, X Yang, J Du, S Men, B Liu, Z Zhang… - 2023 - researchsquare.com
Non-invasive brain stimulation therapy for autism spectrum disorder (ASD) has shown
beneficial effects. Recently, visual sensory stimulation using rhythmic 40 Hz light flicker …

Enhancement of spatial learning by 40 Hz visual stimulation requires parvalbumin interneuron-dependent hippocampal neurogenesis

H Yan, X Deng, Y Wang, S Wu, D Jun, M Yu, B Liu… - bioRxiv, 2024 - biorxiv.org
Acute and short-term rhythmic 40 Hz light flicker stimulation has shown promising results in
alleviating cognitive impairments in mouse models of Alzheimer's disease (AD), stroke, and …