Mechanisms of action of fluvoxamine for COVID-19: a historical review
Y Hashimoto, T Suzuki, K Hashimoto - Molecular psychiatry, 2022 - nature.com
The ongoing coronavirus disease 2019 (COVID-19) pandemic caused by the novel severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) accelerates the discovery of …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) accelerates the discovery of …
The acid sphingomyelinase/ceramide system in COVID-19
J Kornhuber, N Hoertel, E Gulbins - Molecular Psychiatry, 2022 - nature.com
Acid sphingomyelinase (ASM) cleaves sphingomyelin into the highly lipophilic ceramide,
which forms large gel-like rafts/platforms in the plasma membrane. We showed that SARS …
which forms large gel-like rafts/platforms in the plasma membrane. We showed that SARS …
[HTML][HTML] Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics
With more than 5 million fatalities and close to 300 million reported cases, COVID-19 is the
first documented pandemic due to a coronavirus that continues to be a major health …
first documented pandemic due to a coronavirus that continues to be a major health …
SARS-CoV-2 and type 1 diabetes in children in Finland: an observational study
Background Some epidemiological studies have suggested an increase in incidence of type
1 diabetes during the COVID-19 pandemic, however the mechanism (s) behind such an …
1 diabetes during the COVID-19 pandemic, however the mechanism (s) behind such an …
Repurposing antidepressants inhibiting the sphingomyelinase acid/ceramide system against COVID-19: current evidence and potential mechanisms
We read with great interest the correspondence letters of Salles et al.[1] and Stip et al.[2],
following our multicenter observational retrospective study that showed a substantial …
following our multicenter observational retrospective study that showed a substantial …
Patients with psychosis spectrum disorders hospitalized during the COVID-19 pandemic unravel overlooked SARS-CoV-2 past infection clustering with HERV-W ENV …
Epidemiology has repeatedly associated certain infections with a risk of further developing
psychiatric diseases. Such infections can activate retro-transposable genetic elements …
psychiatric diseases. Such infections can activate retro-transposable genetic elements …
Association of fluvoxamine with mortality and symptom resolution among inpatients with COVID-19 in Uganda: a prospective interventional open-label cohort study
BJ Kirenga, L Mugenyi, M Sánchez-Rico, H Kyobe… - Molecular …, 2023 - nature.com
Prior research suggests that fluvoxamine, a selective serotonin reuptake inhibitor (SSRI)
used for the treatment of obsessive-compulsive disorder and major depressive disorder …
used for the treatment of obsessive-compulsive disorder and major depressive disorder …
Antiviral and anti-inflammatory activities of fluoxetine in a SARS-CoV-2 infection mouse model
D Péricat, SA Leon-Icaza, M Sanchez Rico… - International Journal of …, 2022 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic continues to cause significant
morbidity and mortality worldwide. Since a large portion of the world's population is currently …
morbidity and mortality worldwide. Since a large portion of the world's population is currently …
[PDF][PDF] Fluoxetine use is associated with improved survival of patients with COVID-19 pneumonia: A retrospective case-control study.
ZK Németh, A Szucs, J Vitrai, D Juhász… - Clinical Neuroscience …, 2021 - real-j.mtak.hu
Background and purpose–We aimed to investigate the association between fluoxetine use
and the survival of hospitalised coronavirus disease (COVID-19) pneumonia patients …
and the survival of hospitalised coronavirus disease (COVID-19) pneumonia patients …
Medications modulating the acid sphingomyelinase/ceramide system and 28-day mortality among patients with SARS-CoV-2: an observational study
Prior evidence indicates the potential central role of the acid sphingomyelinase
(ASM)/ceramide system in the infection of cells with SARS-CoV-2. We conducted a …
(ASM)/ceramide system in the infection of cells with SARS-CoV-2. We conducted a …