[HTML][HTML] Task-and resting-state fMRI studies in multiple sclerosis: From regions to systems and time-varying analysis. Current status and future perspective

MA Rocca, MM Schoonheim, P Valsasina… - Neuroimage: Clinical, 2022 - Elsevier
Multiple sclerosis (MS) is a neurological disorder affecting the central nervous system and
features extensive functional brain changes that are poorly understood but relate strongly to …

The role of fMRI in the assessment of neuroplasticity in MS: a systematic review

DG Laura, T Silvia, P Nikolaos, P Patrizia - Neural plasticity, 2018 - Wiley Online Library
Neuroplasticity, which is the ability of the brain to adapt to internal and external
environmental changes, physiologically occurs during growth and in response to damage …

Bimanual digit training improves right-hand dexterity in older adults by reactivating declined ipsilateral motor-cortical inhibition

E Naito, T Morita, S Hirose, N Kimura, H Okamoto… - Scientific Reports, 2021 - nature.com
Improving deteriorated sensorimotor functions in older individuals is a social necessity in a
super-aging society. Previous studies suggested that the declined interhemispheric …

The effect of inflammation and its reduction on brain plasticity in multiple sclerosis: MRI evidence

V Tomassini, A d'Ambrosio, N Petsas… - Human brain …, 2016 - Wiley Online Library
Brain plasticity is the basis for systems‐level functional reorganization that promotes
recovery in multiple sclerosis (MS). As inflammation interferes with plasticity, its …

Changes in brain perfusion with training-related visuomotor improvement in MS

E Patitucci, I Lipp, RC Stickland, RG Wise… - Frontiers in Molecular …, 2023 - frontiersin.org
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system. A
better understanding of the mechanisms supporting brain plasticity in MS would help to …

Functional connectivity changes after initial treatment with fingolimod in multiple sclerosis

N Petsas, L De Giglio, V González-Quintanilla… - Frontiers in …, 2019 - frontiersin.org
On the basis of recent functional MRI studies, Multiple Sclerosis (MS) has been interpreted
as a multisystem disconnection syndrome. Compared to normal subjects, MS patients show …

The role of fMRI to assess plasticity of the motor system in MS

P Pantano, N Petsas, F Tona, E Sbardella - Frontiers in Neurology, 2015 - frontiersin.org
Neuroplasticity in the motor system has been extensively investigated by functional MRI
(fMRI) in multiple sclerosis (MS) patients; we report results obtained by both task-related and …

Importance of the primary motor cortex in development of human hand/finger dexterity

E Naito, T Morita, M Asada - Cerebral cortex communications, 2020 - academic.oup.com
Hand/finger dexterity is well-developed in humans, and the primary motor cortex (M1) is
believed to play a particularly important role in it. Here, we show that efficient recruitment of …

Impaired functional connectivity unmasked by simple repetitive motor task in early relapsing-remitting multiple sclerosis

N Petsas, V Tomassini, N Filippini… - … and Neural Repair, 2015 - journals.sagepub.com
Background. Resting brain activity can be modulated by motor tasks to adapt to function. In
multiple sclerosis (MS) patients, altered resting-state functional connectivity (RS-FC) has …

Multidisciplinary rehabilitation is efficacious and induces neural plasticity in multiple sclerosis even when complicated by progressive multifocal leukoencephalopathy

E Groppo, F Baglio, D Cattaneo, E Tavazzi… - Frontiers in …, 2017 - frontiersin.org
A 48-year-old woman with multiple sclerosis (MS), treated with natalizumab for more than
one year without clinical and magnetic resonance imaging (MRI) signs of disease activity …