Drug delivery strategies for antibiofilm therapy

V Choi, JL Rohn, P Stoodley, D Carugo… - Nature Reviews …, 2023 - nature.com
Although new antibiofilm agents have been developed to prevent and eliminate pathogenic
biofilms, their widespread clinical use is hindered by poor biocompatibility and …

Chemotaxis and autoinducer-2 signalling mediate colonization and contribute to co-existence of Escherichia coli strains in the murine gut

L Laganenka, JW Lee, L Malfertheiner… - Nature …, 2023 - nature.com
Bacteria communicate and coordinate their behaviour at the intra-and interspecies levels by
producing and sensing diverse extracellular small molecules called autoinducers …

Deciphering the quorum-sensing lexicon of the gut microbiota

RA Oliveira, V Cabral, I Torcato, KB Xavier - Cell Host & Microbe, 2023 - cell.com
The enduring coexistence between the gut microbiota and the host has led to a symbiotic
relationship that benefits both parties. In this complex, multispecies environment, bacteria …

Host monitoring of quorum sensing during Pseudomonas aeruginosa infection

P Moura-Alves, A Puyskens, A Stinn, M Klemm… - Science, 2019 - science.org
INTRODUCTION The interaction between a bacterial pathogen and its host can be viewed
as an “arms race” in which each participant continuously responds to the evolving strategies …

Challenges and limitations of anti-quorum sensing therapies

P Krzyżek - Frontiers in microbiology, 2019 - frontiersin.org
Quorum sensing (QS) is a mechanism allowing microorganisms to sense population density
and synchronously control genes expression. It has been shown that QS supervises the …

Salmonella Typhimurium infection disrupts but continuous feeding of Bacillus based probiotic restores gut microbiota in infected hens

S Khan, KK Chousalkar - Journal of animal science and biotechnology, 2020 - Springer
Background The gut microbiota plays an important role in the colonisation resistance and
invasion of pathogens. Salmonella Typhimurium has the potential to establish a niche by …

SnapShot: bacterial quorum sensing

MJ Eickhoff, BL Bassler - Cell, 2018 - cell.com
Quorum sensing (QS) is a chemical communication process that bacteria use to orchestrate
group behaviors. QS involves the production, release, and population-wide detection of …

Quorum sensing architecture network in Escherichia coli virulence and pathogenesis

C Mayer, A Borges, SC Flament-Simon… - FEMS Microbiology …, 2023 - academic.oup.com
Escherichia coli is a Gram-negative commensal bacterium of the normal microbiota of
humans and animals. However, several E. coli strains are opportunistic pathogens …

Signal transduction network principles underlying bacterial collective behaviors

AA Bridges, JA Prentice, NS Wingreen… - Annual review of …, 2022 - annualreviews.org
Bacteria orchestrate collective behaviors and accomplish feats that would be unsuccessful if
carried out by a lone bacterium. Processes undertaken by groups of bacteria include …

Surface-attached molecules control Staphylococcus aureus quorum sensing and biofilm development

MK Kim, A Zhao, A Wang, ZZ Brown, TW Muir… - Nature …, 2017 - nature.com
Bacteria use a process called quorum sensing to communicate and orchestrate collective
behaviours, including virulence factor secretion and biofilm formation. Quorum sensing …