[HTML][HTML] Virtual screening and in vitro experimental verification of LuxS inhibitors from natural products for Lactobacillus reuteri

F Meng, F Zhang, Q Chen, M Yang, Y Yang, X Li… - Biomedicine & …, 2022 - Elsevier
The rapid proliferation and colonization of probiotics in the intestines are essential for
human health. Quorum sensing (QS) is a communication mechanism among bacteria, which …

[HTML][HTML] LuxS quorum sensing system and biofilm formation of oral microflora: A short review article

AA Niazy - The Saudi Dental Journal, 2021 - Elsevier
The LuxS quorum sensing system is considered as the main system that most of the oral
bacteria use to communicate in order to create biofilms. Here we identified 11 of the most …

Autoinducer-2 may be a new biomarker for monitoring neonatal necrotizing enterocolitis

CY Fu, LQ Li, T Yang, X She, Q Ai… - Frontiers in Cellular and …, 2020 - frontiersin.org
Autoinducer-2 (AI-2) has a widely accepted role in bacterial intra-and interspecies
communication. Little is known about the relationships between AI-2 and NEC. This study …

Cryo‐EM structures of pentameric autoinducer‐2 exporter from Escherichia coli reveal its transport mechanism

R Khera, AR Mehdipour, JR Bolla, J Kahnt… - The EMBO …, 2022 - embopress.org
Bacteria utilize small extracellular molecules to communicate in order to collectively
coordinate their behaviors in response to the population density. Autoinducer‐2 (AI‐2), a …

Molecular Aspects of the Functioning of Pathogenic Bacteria Biofilm Based on Quorum Sensing (QS) Signal-Response System and Innovative Non-Antibiotic …

E Juszczuk-Kubiak - International Journal of Molecular Sciences, 2024 - mdpi.com
One of the key mechanisms enabling bacterial cells to create biofilms and regulate crucial
life functions in a global and highly synchronized way is a bacterial communication system …

Biochemical mechanisms of pathogen restriction by intestinal bacteria

KJ Rangan, HC Hang - Trends in biochemical sciences, 2017 - cell.com
The intestine is a highly complex ecosystem where many bacterial species interact with
each other and host cells to influence animal physiology and susceptibility to pathogens …

[HTML][HTML] Autoinducer-2 of gut microbiota, a potential novel marker for human colorectal cancer, is associated with the activation of TNFSF9 signaling in macrophages

Q Li, W Peng, J Wu, X Wang, Y Ren, H Li… - …, 2019 - Taylor & Francis
Objectives: The interaction between the quorum sensing (QS) molecules of gut microbiota
and the immunity of colorectal cancer (CRC) has not been investigated before. Methods: We …

Host control of the microbiome: Mechanisms, evolution, and disease

J Wilde, E Slack, KR Foster - Science, 2024 - science.org
Many species, including humans, host communities of symbiotic microbes. There is a vast
literature on the ways these microbiomes affect hosts, but here we argue for an increased …

Intestinal interplay of quorum sensing molecules and human receptors

K Krasulova, P Illes - Biochimie, 2021 - Elsevier
Human gut is in permanent contact with microorganisms that play an important role in many
physiological processes including metabolism and immunologic activity. These …

Role of interspecies bacterial communication in the virulence of pathogenic bacteria

R Banerji, P Kanojiya, SD Saroj - Critical reviews in microbiology, 2020 - Taylor & Francis
Bacteria live in a polymicrobial community where it interacts with biotic and abiotic factors
using specific signalling molecules. Acyl homoserine lactones, autoinducing peptides …