This review aims to survey the current state of mechanotransduction in vascular smooth
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …

Mechanotransduction, the conversion of physical forces into biochemical signals, is
essential for various physiological processes such as the conscious sensations of touch and …

Potassium channels ubiquitously exist in nearly all kingdoms of life and perform diverse but
important functions. Since the first atomic structure of a prokaryotic potassium channel …

Two-pore domain K+ (K2P) channels give rise to leak (also called background) K+ currents.
The well-known role of background K+ currents is to stabilize the negative resting …

The ability to control cell volume is pivotal for cell function. Cell volume perturbation elicits a
wide array of signaling events, leading to protective (eg, cytoskeletal rearrangement) and …

Mechanosensitive ion channels underlie neuronal responses to physical forces in the
sensation of touch, hearing, and other mechanical stimuli. The fundamental basis of force …

Activation of mechanosensitive ion channels by physical force underlies many physiological
processes including the sensation of touch, hearing and pain,,,,. TRAAK (also known as …

Ultrasound modulates the electrical activity of excitable cells and offers advantages over
other neuromodulatory techniques; for example, it can be noninvasively transmitted through …

TRAAK channels, members of the two–pore domain K+ (potassium ion) channel family K2P,
are expressed almost exclusively in the nervous system and control the resting membrane …

We possess an acute sense of temperature. Most of us seek shade on a hot summer day,
prefer a warm shower to a cold one, and enjoy red wines served at a temperature of 15–18° …