The endothelium, a cellular monolayer lining the blood vessel wall, plays a critical role in
maintaining multiorgan health and homeostasis. Endothelial functions in health include …

Maintenance of endothelial cell integrity is an important component of human health and
disease since the endothelium can perform various functions including regulation of …

Extracellular vesicles (EV) are secretory membranous elements used by cells to transport
proteins, lipids, mRNAs, and microRNAs (miRNAs). While their existence has been known …

Atherosclerosis and its attendant clinical complications, such as myocardial infarction,
stroke, and peripheral artery disease, are the leading cause of morbidity and mortality in …

The vascular endothelium is an interface between the blood stream and the vessel wall.
Changes in this single cell layer of the artery wall are believed of primary importance in the …

We describe an update of the miRBase database (http://www. mirbase. org/), the primary
microRNA sequence repository. The latest miRBase release (v20, June 2013) contains 24 …

Arterial stiffness predicts an increased risk of cardiovascular events. Inflammation plays a
major role in large arteries stiffening, related to atherosclerosis, arteriosclerosis, endothelial …

A central function of the vascular endothelium is to serve as a barrier between the blood and
the surrounding tissue of the body. At the same time, solutes and cells have to pass the …

Research showing that microRNAs (miRNAs) are versatile regulators of gene expression
has instigated tremendous interest in cardiovascular research. The overwhelming majority of …

A biomarker can be a substance or structure measured in body parts, fluids or products that
can affect or predict disease incidence. As age-related macular degeneration (AMD) is the …