Neuro‐oncology surgery would benefit from detailed intraoperative tissue characterization
provided by noncontact, contrast‐agent‐free, noninvasive optical imaging methods. In …

The visualization of protoporphyrin IX (PPIX) fluorescence with the help of surgical
microscopes during 5-aminolevulinic acid-mediated fluorescence-guided resection (FGR) of …

Autofluorescence spectroscopy has emerged in recent years as a powerful tool to report
label-free contrast between normal and diseased tissues, both in vivo and ex vivo. We report …

Abstract Knowledge of temperature-induced changes of skin optical properties is required
for accurate dosimetry of photothermal treatments. We determined and compared in vivo …

Complete resection of the tumor is important for survival in glioma patients. Even if the gross
total resection was achieved, left-over micro-scale tissue in the excision cavity risks …

Among all the tumors of the central nervous system (CNS), glioma are the most deadly and
the most malignant. Surgical resection is the standard therapeutic method to treat this type of …

Significance: Orthopedic surgery currently comprises over 1.5 million cases annually in the
United States alone and is growing rapidly with aging populations. Emerging optical sensing …

Meningioma is the most common primary intracranial extra-axial tumor. Total surgical
removal is the standard therapeutic method to treat this type of brain tumors. However, the …

Motivation Online assessment of tumor characteristics during surgery is important and has
the potential to establish an intra-operative surgeon feedback mechanism. With the …

Fluorescence-guided surgery has emerged as a vital tool for tumour resection procedures.
As well as intraoperative tumour visualisation, 5-ALA-induced PpIX provides an avenue for …