[HTML][HTML] Relationship between amyloid-β deposition and blood–brain barrier dysfunction in Alzheimer's disease

D Wang, F Chen, Z Han, Z Yin, X Ge… - Frontiers in Cellular …, 2021 - frontiersin.org
Amyloid-β (Aβ) is the predominant pathologic protein in Alzheimer's disease (AD). The
production and deposition of Aβ are important factors affecting AD progression and …

[HTML][HTML] Aptamer-engineered (nano) materials for theranostic applications

N Rabiee, S Chen, S Ahmadi, RN Veedu - Theranostics, 2023 - ncbi.nlm.nih.gov
A diverse array of organic and inorganic materials, including nanomaterials, has been
extensively employed in multifunctional biomedical applications. These applications …

[HTML][HTML] Small-molecule theranostics in Alzheimer's disease

Á Sarabia-Vallejo, P López-Alvarado… - European Journal of …, 2023 - Elsevier
Alzheimer's Disease (AD) remains one of the most challenging health-related issues for our
society. It is becoming increasingly prevalent, especially in developed countries, due to the …

[HTML][HTML] Aβ plaques

LC Walker - Free neuropathology, 2020 - ncbi.nlm.nih.gov
Aβ plaques are one of the two lesions in the brain that define the neuropathological
diagnosis of Alzheimer's disease. Plaques are highly diverse structures; many of them …

[HTML][HTML] Potential implications of miRNAs in the pathogenesis, diagnosis, and therapeutics of Alzheimer's disease

L Wang, X Shui, Y Diao, D Chen, Y Zhou… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a complex multifactorial disorder that poses a substantial
burden on patients, caregivers, and society. Considering the increased aging population …

[HTML][HTML] Metallic nanostructure-based aptasensors for robust detection of proteins

N Rabiee, S Ahmadi, K Rahimizadeh, S Chen… - Nanoscale …, 2024 - pubs.rsc.org
There is a significant need for rapid, cost-effective, and highly sensitive protein target
detection, particularly in the fields of food, environmental monitoring, and healthcare. The …

Nanoparticles-assisted aptamer biosensing for the detection of environmental pathogens

K Rahimizadeh, Q ul ain Zahra, S Chen, BT Le… - Environmental …, 2023 - Elsevier
Given the importance of public health, it is crucial to develop quick, targeted, highly
sensitive, and accurate technologies to monitor pathogenic microbes in response to the …

[HTML][HTML] Mangosteen pericarp and its bioactive xanthones: Potential therapeutic value in Alzheimer's disease, Parkinson's disease, and depression with …

HTT Do, J Cho - International journal of molecular sciences, 2020 - mdpi.com
Alzheimer's disease (AD), Parkinson's disease (PD), and depression are growing burdens
for society globally, partly due to a lack of effective treatments. Mangosteen (Garcinia …

[HTML][HTML] Contribution of A-to-I RNA editing, M6A RNA Methylation, and Alternative Splicing to physiological brain aging and neurodegenerative diseases

V Tassinari, P La Rosa, E Guida, A Colopi… - Mechanisms of ageing …, 2023 - Elsevier
Aging is a physiological and progressive phenomenon in all organisms' life cycle,
characterized by the accumulation of degenerative processes triggered by several …

Precision medicine through antisense oligonucleotide-mediated exon skipping

D Li, FL Mastaglia, S Fletcher, SD Wilton - Trends in Pharmacological …, 2018 - cell.com
Clinical implementation of two recently approved antisense RNA therapeutics–Exondys51®
to treat Duchenne muscular dystrophy (Duchenne MD) and Spinraza® as a treatment for …