To defense harmful stimuli or maintain the immune homeostasis, the body produces and
recruits a superfamily of cytokines such as interleukins, interferons, chemokines etc. Among …

CC chemokines (or β-chemokines) are 28 chemotactic cytokines with an N-terminal CC
domain that play an important role in immune system cells, such as CD4+ and CD8+ …

Atherosclerosis is a long-term, chronic inflammatory disease of the vessel wall leading to the
formation of occlusive or rupture-prone lesions in large arteries. Complications of …

Background Rheumatoid arthritis (RA) is a chronic systemic autoimmune disorder
characterized by inflammatory cell infiltration, leading to persistent synovitis and joint …

Perivascular adipose tissue (PVAT) plays a critical role in the pathogenesis of
cardiovascular disease. In vascular pathologies, perivascular adipose tissue increases in …

Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic. Clinical evidence …

Despite the widespread observations on the osteogenic effects of magnesium ion (Mg2+),
the diverse roles of Mg2+ during bone healing have not been systematically dissected …

Background: Immune checkpoint inhibitors (ICIs) are monoclonal antibodies used to activate
the immune system against tumor cells. Despite therapeutic benefits, ICIs have the potential …

Liver malignancies are among the tumor types that are resistant to immune checkpoint
inhibition therapy. Tumor‐associated macrophages (TAMs) are highly enriched and play a …

Recent studies have emphasized the role of perivascular inflammation in cardiovascular
disease. We studied mechanisms of perivascular leukocyte infiltration in angiotensin II (Ang …