Modifications of epigenetic factors affect our lives and can give important information
regarding one's state of health. In cancer, epigenetic modifications play a crucial role, as …

In the era of personalized therapy, precise targeting of subcellular organelles holds great
promise for cancer modality. Taking into consideration that lysosome represents the …

Despite the challenges posed by drug resistance and side effects, chemotherapy remains a
pivotal strategy in cancer treatment. A key issue in this context is macroautophagy …

The larvae of black soldier fly (BSFL) convert organic waste into insect proteins used as
feedstuff for livestock and aquaculture. BSFL production performance is considerably …

Alcohol intake provokes severe organ injuries including alcoholic cardiomyopathy with
hallmarks of cardiac remodeling and contractile defects. This study examined the toxicity of …

The crucial role played by the oncogenic expression of TP53, stemming from mutation or
amyloid formation, in various human malignancies has been extensively studied over the …

Objective The relationships between circulating inflammatory proteins and COVID-19 have
been observed in previous cohorts. However, it is not unclear which circulating inflammatory …

The mechanistic target of rapamycin (mTOR) is a serine/threonine kinase that functions via
its discrete binding partners to form two multiprotein complexes, mTOR complex 1 and 2 …

Cells respond to DNA damage by activating a complex array of signaling networks, which
include the AMPK and mTOR pathways. After DNA double-strand breakage, ATM, a core …

Lysosomes are crucial organelles responsible for the degradation of cytosolic materials and
bulky organelles, thereby facilitating nutrient recycling and cell survival. However, lysosome …