Efficacy, safety, and immunogenicity of an oral recombinant Helicobacter pylori vaccine in children in China: a randomised, double-blind, placebo-controlled, phase 3 …

M Zeng, XH Mao, JX Li, WD Tong, B Wang, YJ Zhang… - The Lancet, 2015 - thelancet.com
Background Helicobacter pylori is one of the most common gastric pathogens, affecting at
least half the world's population, and is strongly associated with gastritis, peptic ulcer, gastric …

Rational Helicobacter pylori therapy: evidence-based medicine rather than medicine-based evidence

DY Graham, YC Lee, MS Wu - Clinical Gastroenterology and Hepatology, 2014 - Elsevier
Data are available such that choice of Helicobacter pylori therapy for an individual patient
can be reliably predicted. Here, treatment success is defined as a cure rate of 90% or …

Probiotics as the live microscopic fighters against Helicobacter pylori gastric infections

M Keikha, M Karbalaei - BMC gastroenterology, 2021 - Springer
Background Helicobacter pylori (H. pylori) is the causative agent of stomach diseases such
as duodenal ulcer and gastric cancer, in this regard incomplete eradication of this bacterium …

[HTML][HTML] Diagnosis and management of high risk group for gastric cancer

H Yoon, N Kim - Gut and liver, 2015 - ncbi.nlm.nih.gov
Gastric cancer is associated with high morbidity and mortality worldwide. To reduce the
socioeconomic burden related to gastric cancer, it is very important to identify and manage …

Helicobacter pylori eradication cannot reduce the risk of gastric cancer in patients with intestinal metaplasia and dysplasia: evidence from a meta-analysis

HN Chen, Z Wang, X Li, ZG Zhou - Gastric cancer, 2016 - Springer
Abstract Background The effect of Helicobacter pylori (H. pylori) eradication on gastric
cancer (GC) prevention is controversial. Intestinal metaplasia (IM) seems to be a “point of no …

Reversibility of atrophic gastritis and intestinal metaplasia after Helicobacter pylori eradication ‐ a prospective study for up to 10 years

YJ Hwang, N Kim, HS Lee, JB Lee… - Alimentary …, 2018 - Wiley Online Library
Background Atrophic gastritis and intestinal metaplasia are premalignant conditions for
gastric cancer. Their reversibility by Helicobacter pylori eradication remains controversial …

Gastric cancer as preventable disease

M Rugge, RM Genta, F Di Mario, EM El-Omar… - Clinical …, 2017 - Elsevier
Gastric cancer, 1 of the 5 most common causes of cancer death, is associated with a 5-year
overall survival rate less than 30%. A minority of cancers occurs as part of syndromic …

[HTML][HTML] Diagnosis of Helicobacter pylori by invasive test: histology

JY Lee, N Kim - Annals of translational medicine, 2015 - ncbi.nlm.nih.gov
The accurate detection of Helicobacter pylori (H. pylori), a major cause of gastric cancer, is
essential for managing infected patients. Among various diagnostic methods, histology plays …

Systematic review: the effects of long‐term proton pump inhibitor use on serum gastrin levels and gastric histology

L Lundell, M Vieth, F Gibson, P Nagy… - Alimentary …, 2015 - Wiley Online Library
Background Proton pump inhibitors (PPI s) have a well‐established safety profile. However,
concerns have been raised about a potential relationship between PPI‐induced …

[HTML][HTML] A review of Helicobacter pylori diagnosis, treatment, and methods to detect eradication

E Garza-González, GI Perez-Perez… - World journal of …, 2014 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) affects nearly half of the world's population and, thus, is one of
the most frequent and persistent bacterial infections worldwide. H. pylori is associated with …