Insertion sequences (ISs) constitute an important component of most bacterial genomes.
Over 500 individual ISs have been described in the literature to date, and many more are …

Antimicrobial resistance in clinically important microbes has emerged as an unmet
challenge in global health. Extensively drug-resistant bacterial pathogens have cropped up …

Like many eukaryotes, bacteria make widespread use of postreplicative DNA methylation for
the epigenetic control of DNA-protein interactions. Unlike eukaryotes, however, bacteria use …

This communication reports the development of an efficient in vitro transposition system for
Tn5. A key component of this system was the use of hyperactive mutant transposase. The …

Background. Based on the organization of 10 amino acid domains present in MTases, Dam
is classified in the α group (Fig. 1)(46). Dam homologues are widespread among enteric …

A notable feature of transposable elements—segments of DNA that can move from one
position to another in genomes—is that they are highly prevalent, despite the fact that their …

Transposable DNA elements occur naturally in the genomes of nearly all species of
prokaryotes. A proposal for a uniform transposable element nomenclature was published …

Transposable elements are discrete mobile DNA segments that can insert into
nonhomologous target sites. Diverse patterns of target site selectivity are observed: Some …

Sulfolobus islandicus is a model microorganism in the TACK superphylum of the Archaea, a
key lineage in the evolutionary history of cells. Here we report a genome-wide identification …

This chapter is an update of a survey of insertion sequences (ISs) published in 1998.
Researchers have retained the same basic structure: a first section including some key …