Targeting inflammation to treat diabetic kidney disease: the road to 2030
S Rayego-Mateos, RR Rodrigues-Diez… - Kidney international, 2023 - Elsevier
Diabetic kidney disease (DKD) is one of the fastest growing causes of chronic kidney
disease and associated morbidity and mortality. Preclinical research has demonstrated the …
disease and associated morbidity and mortality. Preclinical research has demonstrated the …
Novel pharmacological interventions for diabetic kidney disease
SK Tan, JA Pinzon-Cortes… - Current Opinion in …, 2024 - journals.lww.com
Renal specific outcome trials have become more popular and are increasing the available
armamentarium to diminish the progression of renal decline in patients at greater risk of end …
armamentarium to diminish the progression of renal decline in patients at greater risk of end …
[HTML][HTML] Is clinical trial data showing positive progress for the treatment of diabetic kidney disease?
Seng Kiong Tan, Department of Diabetes, Central Clinical School, Monash University, Level
5, 99 Commercial Rd Melbourne, Melbourne, VIC 3004, Australia Diabetes Centre, Khoo …
5, 99 Commercial Rd Melbourne, Melbourne, VIC 3004, Australia Diabetes Centre, Khoo …
[HTML][HTML] Recent advancements in targeted protein knockdown technologies—emerging paradigms for targeted therapy
M Joshi, P Dey, A De - Exploration of Targeted Anti-tumor Therapy, 2023 - ncbi.nlm.nih.gov
A generalized therapeutic strategy for various disease conditions, including cancer, is to
deplete or inactivate harmful protein targets. Various forms of protein or gene silencing …
deplete or inactivate harmful protein targets. Various forms of protein or gene silencing …
Comparative Multi-omic Mapping of Human Pancreatic Islet Endoplasmic Reticulum and Cytokine Stress Responses Provides Insights into Type 2 Diabetes Genetics
EK Sokolowski, R Kursawe, V Selvam, RM Bhuiyan… - bioRxiv, 2024 - biorxiv.org
Endoplasmic reticulum (ER) and inflammatory stress responses are two pathophysiologic
factors contributing to islet dysfunction and failure in Type 2 Diabetes (T2D). However, how …
factors contributing to islet dysfunction and failure in Type 2 Diabetes (T2D). However, how …