Background Psychiatric comorbidity is known to impact upon use of nonpsychiatric health
services. The aim of this systematic review and meta-analysis was to assess the specific …

Importance Opioid-related mortality and national prescribing guidelines have led to tapering
of doses among patients prescribed long-term opioid therapy for chronic pain. There is …

Importance While current reports suggest that a disproportionate share of US coronavirus
disease 2019 (COVID-19) cases and deaths are among Black residents, little information is …

Importance Broad-spectrum antibiotics are recommended for all patients with suspected
sepsis to minimize the risk of undertreatment. However, little is known regarding the net …

Background To better understand the impact of the COVID-19 pandemic on hospital
healthcare, we studied activity in the emergency department (ED) and acute medicine …

Background Pregnant women are potentially a high-risk population during infectious
disease outbreaks such as COVID-19, because of physiologic immune suppression in …

Objectives Morbidity is an important risk factor for mortality and a variety of morbidity
measures have been developed to predict patients' health outcomes. The objective of this …

Comorbidity scores are extensively used in observational medical research studies to avoid
potential bias when the burden of disease could be confounding the association of interest …

Importance Bloodstream infections (BSIs) are a major public health problem associated with
high morbidity. Little evidence exists regarding the epidemiology of BSIs and the use of …

Introduction Recent US trends demonstrate sharp rises in adverse opioid-related health
outcomes, including opioid use disorder (OUD), overdose, and death. Yet few affected …