The hippocampal sharp wave–ripple in memory retrieval for immediate use and consolidation

HR Joo, LM Frank - Nature Reviews Neuroscience, 2018 - nature.com
Various cognitive functions have long been known to require the hippocampus. Recently,
progress has been made in identifying the hippocampal neural activity patterns that …

Navigating for reward

M Sosa, LM Giocomo - Nature Reviews Neuroscience, 2021 - nature.com
An organism's survival can depend on its ability to recall and navigate to spatial locations
associated with rewards, such as food or a home. Accumulating research has revealed that …

Hippocampal CA2 sharp-wave ripples reactivate and promote social memory

A Oliva, A Fernández-Ruiz, F Leroy, SA Siegelbaum - Nature, 2020 - nature.com
The consolidation of spatial memory depends on the reactivation ('replay') of hippocampal
place cells that were active during recent behaviour. Such reactivation is observed during …

On the integration of space, time, and memory

H Eichenbaum - Neuron, 2017 - cell.com
The hippocampus is famous for mapping locations in spatially organized environments, and
several recent studies have shown that hippocampal networks also map moments in …

Hippocampal replay reflects specific past experiences rather than a plan for subsequent choice

AK Gillespie, DAA Maya, EL Denovellis, DF Liu… - Neuron, 2021 - cell.com
Executing memory-guided behavior requires storage of information about experience and
later recall of that information to inform choices. Awake hippocampal replay, when …

High-density, long-lasting, and multi-region electrophysiological recordings using polymer electrode arrays

JE Chung, HR Joo, JL Fan, DF Liu, AH Barnett, S Chen… - Neuron, 2019 - cell.com
The brain is a massive neuronal network, organized into anatomically distributed sub-
circuits, with functionally relevant activity occurring at timescales ranging from milliseconds …

Constant sub-second cycling between representations of possible futures in the hippocampus

K Kay, JE Chung, M Sosa, JS Schor, MP Karlsson… - Cell, 2020 - cell.com
Cognitive faculties such as imagination, planning, and decision-making entail the ability to
represent hypothetical experience. Crucially, animal behavior in natural settings implies that …

Heterogeneity within classical cell types is the rule: lessons from hippocampal pyramidal neurons

MS Cembrowski, N Spruston - Nature Reviews Neuroscience, 2019 - nature.com
The mechanistic operation of brain regions is often interpreted by partitioning constituent
neurons into 'cell types'. Historically, such cell types were broadly defined by their …

Dynamics of awake hippocampal-prefrontal replay for spatial learning and memory-guided decision making

JD Shin, W Tang, SP Jadhav - Neuron, 2019 - cell.com
Spatial learning requires remembering and choosing paths to goals. Hippocampal place
cells replay spatial paths during immobility in reverse and forward order, offering a potential …

Imagination as a fundamental function of the hippocampus

AE Comrie, LM Frank, K Kay - … Transactions of the …, 2022 - royalsocietypublishing.org
Imagination is a biological function that is vital to human experience and advanced
cognition. Despite this importance, it remains unknown how imagination is realized in the …