As reperfusion therapies have become more widely used in acute myocardial infarction
patients, ischemia-induced myocardial damage has been markedly reduced, but reperfusion …

Coronary microvascular disease (CMD), which affects the arterioles and capillary
endothelium that regulate myocardial perfusion, is an increasingly recognized source of …

Despite successful clot retrieval in large vessel occlusion stroke,∼ 50% of patients have an
unfavorable clinical outcome. The mechanisms underlying this functional reperfusion failure …

Background and Objectives The relevance of impaired microvascular tissue-level
reperfusion despite complete upstream macrovascular angiographic reperfusion (no-reflow) …

Background Platelet‐to‐lymphocyte ratio (PLR) is a haematological index which reflects
increased level of inflammation and thrombosis. We aimed to summarize the potential …

Currently, guidelines recommend the uptake of high-dose statins before and after
percutaneous coronary intervention (PCI) in patients with acute coronary syndrome …

The no-reflow phenomenon following primary percutaneous coronary intervention (PPCI) in
acute ST-elevation myocardial infarction (STEMI) patients is a predictor of unfavorable …

Pericytes contract during myocardial ischemia resulting in capillary constriction and no
reflow. Reversing pericyte contraction pharmacologically reduces no reflow and infarct size …

Acute ischemic stroke (AIS) afflicts millions of individuals worldwide. Despite the
advancements in thrombolysis and thrombectomy facilitating proximal large artery …

Significance: Regular exercise training can reduce myocardial damage caused by acute
ischemia/reperfusion (I/R). Exercise can reproduce the phenomenon of ischemic …