Long covid—mechanisms, risk factors, and management

H Crook, S Raza, J Nowell, M Young, P Edison - bmj, 2021 - bmj.com
Since its emergence in Wuhan, China, covid-19 has spread and had a profound effect on
the lives and health of people around the globe. As of 4 July 2021, more than 183 million …

[HTML][HTML] Psychiatric and neuropsychiatric sequelae of COVID-19–A systematic review

TM Schou, S Joca, G Wegener… - Brain, behavior, and …, 2021 - Elsevier
It has become evident that coronavirus disease 2019 (COVID-19) has a multi-organ
pathology that includes the brain and nervous system. Several studies have also reported …

[HTML][HTML] Long-term respiratory and neurological sequelae of COVID-19

F Wang, RM Kream, GB Stefano - Medical science monitor …, 2020 - ncbi.nlm.nih.gov
Since the initial reports of coronavirus disease 2019 (COVID-19) in China in late 2019,
infections from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have …

Could SARS-CoV-2 spike protein be responsible for long-COVID syndrome?

TC Theoharides - Molecular Neurobiology, 2022 - Springer
SARS-CoV-2 infects cells via its spike protein binding to its surface receptor on target cells
and results in acute symptoms involving especially the lungs known as COVID-19. However …

[HTML][HTML] Covid-19 hyperinflammation and post-Covid-19 illness may be rooted in mast cell activation syndrome

LB Afrin, LB Weinstock, GJ Molderings - International journal of infectious …, 2020 - Elsevier
Abstract Objectives One-fifth of Covid-19 patients suffer a severe course of Covid-19
infection; however, the specific causes remain unclear. Mast cells (MCs) are activated by …

Specialized pro-resolving mediator network: an update on production and actions

N Chiang, CN Serhan - Essays in Biochemistry, 2020 - portlandpress.com
Today, persistent and uncontrolled inflammation is appreciated to play a pivotal role in many
diseases, such as cardiovascular diseases, neurodegenerative diseases, metabolic …

Long‐COVID syndrome‐associated brain fog and chemofog: Luteolin to the rescue

TC Theoharides, C Cholevas, K Polyzoidis… - Biofactors, 2021 - Wiley Online Library
COVID‐19 leads to severe respiratory problems, but also to long‐COVID syndrome
associated primarily with cognitive dysfunction and fatigue. Long‐COVID syndrome …

Neurological complications and infection mechanism of SARS-COV-2

D Wan, T Du, W Hong, L Chen, H Que, S Lu… - Signal Transduction and …, 2021 - nature.com
Abstract Currently, SARS-CoV-2 has caused a global pandemic and threatened many lives.
Although SARS-CoV-2 mainly causes respiratory diseases, growing data indicate that SARS …

SARS-CoV-2 spike S1 subunit induces neuroinflammatory, microglial and behavioral sickness responses: Evidence of PAMP-like properties

MG Frank, KH Nguyen, JB Ball, S Hopkins… - Brain, behavior, and …, 2022 - Elsevier
SARS-CoV-2 infection produces neuroinflammation as well as neurological, cognitive (ie,
brain fog), and neuropsychiatric symptoms (eg, depression, anxiety), which can persist for …

The role of cytokines and chemokines in severe acute respiratory syndrome coronavirus 2 infections

RJ Hsu, WC Yu, GR Peng, CH Ye, SY Hu… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in countless
infections and caused millions of deaths since its emergence in 2019. Coronavirus disease …