Second-line HIV treatment failure in sub-Saharan Africa: A systematic review and meta-analysis
Background Increased second-line antiretroviral therapy (ART) failure rate narrows future
options for HIV/AIDS treatment. It has critical implications in resource-limited settings; …
options for HIV/AIDS treatment. It has critical implications in resource-limited settings; …
Effectiveness of protease inhibitor/nucleos (t) ide reverse transcriptase inhibitor–based second-line antiretroviral therapy for the treatment of human immunodeficiency …
Abstract Background In sub-Saharan Africa, 25.5 million people are living with human
immunodeficiency virus (HIV), representing 70% of the global total. The need for second-line …
immunodeficiency virus (HIV), representing 70% of the global total. The need for second-line …
Enhanced adherence counselling and viral load suppression in HIV seropositive patients with an initial high viral load in Harare, Zimbabwe: operational issues
T Bvochora, S Satyanarayana, KC Takarinda, H Bara… - PloS one, 2019 - journals.plos.org
Background In people living with HIV (PLHIV) who are on anti-retroviral therapy (ART), it is
essential to identify persons with high blood viral loads (VLs)(≥ 1000 copies/ml), provide …
essential to identify persons with high blood viral loads (VLs)(≥ 1000 copies/ml), provide …
Risks and benefits of dolutegravir-and efavirenz-based strategies for South African women with HIV of child-bearing potential: a modeling study
Background: Dolutegravir is superior to efavirenz for HIV antiretroviral therapy (ART) but
may be associated with an increased risk for neural tube defects (NTDs) in newborns if used …
may be associated with an increased risk for neural tube defects (NTDs) in newborns if used …
A cascade of interventions to promote adherence to antiretroviral therapy in African countries
Abstract Purpose of Review We reviewed interventions to improve uptake and adherence to
antiretroviral therapy (ART) in African countries in the Treat All era. Recent Findings ART …
antiretroviral therapy (ART) in African countries in the Treat All era. Recent Findings ART …
Third-line antiretroviral therapy program in the South African public sector: cohort description and virological outcomes
M Moorhouse, G Maartens, WDF Venter… - JAIDS Journal of …, 2019 - journals.lww.com
Background: The World Health Organization recommends that antiretroviral therapy (ART)
programs in resource-limited settings develop third-line ART policies. South Africa …
programs in resource-limited settings develop third-line ART policies. South Africa …
Third-line antiretroviral therapy in low-income and middle-income countries (ACTG A5288): a prospective strategy study
B Grinsztejn, MD Hughes, J Ritz, R Salata… - The lancet HIV, 2019 - thelancet.com
Background Antiretroviral therapy (ART) management is challenging for individuals in
resource-limited settings presenting for third-line treatment because of complex resistance …
resource-limited settings presenting for third-line treatment because of complex resistance …
[HTML][HTML] HIV-1 drug resistance in adults and adolescents on protease inhibitor-based antiretroviral therapy in KwaZulu-Natal Province, South Africa
Objectives In low–middle-income countries, increasing levels of HIV drug resistance
(HIVDR) on second-line protease inhibitor (PI)-based regimens are a cause for concern …
(HIVDR) on second-line protease inhibitor (PI)-based regimens are a cause for concern …
HIV-1 drug resistance and third-line therapy outcomes in patients failing second-line therapy in Zimbabwe
C Chimbetete, D Katzenstein, T Shamu… - Open forum …, 2018 - academic.oup.com
Objectives To analyze the patterns and risk factors of HIV drug resistance mutations among
patients failing second-line treatment and to describe early treatment responses to …
patients failing second-line treatment and to describe early treatment responses to …
Barriers and facilitators to viral load suppression among people living with HIV following intensive adherence counseling in Kampala, Uganda: A qualitative study
We explored the barriers and facilitators to viral load (VL) suppression after three or more
intensive adherence counseling (IAC) sessions among adolescents and adults living with …
intensive adherence counseling (IAC) sessions among adolescents and adults living with …