[HTML][HTML] Recent advances on small molecules in osteogenic differentiation of stem cells and the underlying signaling pathways
Bone-related diseases are major contributors to morbidity and mortality in elderly people
and the current treatments result in insufficient healing and several complications. One of the …
and the current treatments result in insufficient healing and several complications. One of the …
Dental pulp stem cells for bone tissue engineering: a literature review
X Bai, R Cao, D Wu, H Zhang, F Yang… - Stem Cells …, 2023 - Wiley Online Library
Bone tissue engineering (BTE) is a promising approach for repairing and regenerating
damaged bone tissue, using stem cells and scaffold structures. Among various stem cell …
damaged bone tissue, using stem cells and scaffold structures. Among various stem cell …
[HTML][HTML] In situ self-assembled organoid for osteochondral tissue regeneration with dual functional units
Z Yang, B Wang, W Liu, X Li, K Liang, Z Fan, JJ Li… - Bioactive Materials, 2023 - Elsevier
The regeneration of hierarchical osteochondral units is challenging due to difficulties in
inducing spatial, directional and controllable differentiation of mesenchymal stem cells …
inducing spatial, directional and controllable differentiation of mesenchymal stem cells …
Melatonin functions as a broad‐spectrum antifungal by targeting a conserved pathogen protein kinase
R Li, R Bi, H Cai, J Zhao, P Sun, W Xu… - Journal of Pineal …, 2023 - Wiley Online Library
Melatonin is a low‐cost natural small indole molecule with versatile biological functions.
However, melatonin's fungicidal potential has not been fully exploited, and the mechanism …
However, melatonin's fungicidal potential has not been fully exploited, and the mechanism …
[HTML][HTML] Heterogeneity of in vitro expanded mesenchymal stromal cells and strategies to improve their therapeutic actions
L Olmedo-Moreno, Y Aguilera, C Baliña-Sánchez… - Pharmaceutics, 2022 - mdpi.com
Beneficial properties of mesenchymal stromal cells (MSCs) have prompted their use in
preclinical and clinical research. Accumulating evidence has been provided for the …
preclinical and clinical research. Accumulating evidence has been provided for the …
Melatonin and bone-related diseases: an updated mechanistic overview of current evidence and future prospects
Purpose Bone diseases account for an enormous cost burden on health systems. Bone
disorders are considered as age-dependent diseases. The aging of world population has …
disorders are considered as age-dependent diseases. The aging of world population has …
[HTML][HTML] Antioxidant materials in oral and maxillofacial tissue regeneration: a narrative review of the literature
Oral and maxillofacial tissue defects caused by trauma, tumor reactions, congenital
anomalies, ischemic diseases, infectious diseases, surgical resection, and odontogenic …
anomalies, ischemic diseases, infectious diseases, surgical resection, and odontogenic …
The role of melatonin in bone regeneration: A review of involved signaling pathways
F Malakoti, F Zare, R Zarezadeh, AR Sadigh… - Biochimie, 2022 - Elsevier
Increasing bone resorption followed by decreasing bone mineralization are hallmarks of
bone degeneration, which mostly occurs in the elderly population and post-menopausal …
bone degeneration, which mostly occurs in the elderly population and post-menopausal …
[HTML][HTML] Physicochemical Characterization, Biocompatibility, and Antibacterial Properties of CMC/PVA/Calendula officinalis Films for Biomedical Applications
WH Huang, CY Hung, PC Chiang, H Lee, IT Lin, PC Lai… - Polymers, 2023 - mdpi.com
This study reports a carboxymethyl cellulose (CMC)/polyvinyl alcohol (PVA) composite film
that incorporates Calendula officinalis (CO) extract for biomedical applications. The …
that incorporates Calendula officinalis (CO) extract for biomedical applications. The …
[HTML][HTML] Melatonin-mediated FKBP4 downregulation protects against stress-induced neuronal mitochondria dysfunctions by blocking nuclear translocation of GR
MJ Kim, GE Choi, CW Chae, JR Lim, YH Jung… - Cell Death & …, 2023 - nature.com
The physiological crosstalk between glucocorticoid and melatonin maintains neuronal
homeostasis in regulating circadian rhythms. However, the stress-inducing level of …
homeostasis in regulating circadian rhythms. However, the stress-inducing level of …