Glycosyltransferases (GTs) catalyze the transfer of active monosaccharide donors to
carbohydrates to create a wide range of oligosaccharide structures. GTs display strong …

Human milk (HM) is considered the best source of nutrition for infant growth and health. This
nourishment is unique and changes constantly during lactation to adapt to the physiological …

Oral administration of chitooligosaccharides (COS) has been reported to alleviate colitis in
mice. However, the mechanism of action of COS with specific polymerization degree on gut …

Human milk oligosaccharides (HMOs) promote adequate intestinal microbiota development
and favor the immune system's maturation and cognitive development. In addition to non …

Highlights•Microbiota-directed fiber with a discrete structure is proposed as targeted
prebiotics.•The prebiotics paradigm shifts to target next-generation probiotics and …

Simple Summary The gastrointestinal tract (GIT) microbiota refers to the collection of
microorganisms that colonize the GIT. The composition and diversity of the GIT microbiota …

Food allergy (FA) has become a prominent problem in public health. 2′-Fucosyllactose
(2′-FL) was reported to alleviate FA symptoms; however, the regulatory mechanism is still …

ABSTRACT Lacto-N-tetraose (LNT) is one of the most important components of human milk
oligosaccharides, which has various beneficial health effects. β-Galactosidase is an …

Abstract Lacto-N-fucopentaose I (LNFP I) is the second most abundant fucosylated human
milk oligosaccharide (HMO) in breast milk after 2′-fucosyllactose (2′-FL). Studies have …

Despite their many important physiological functions, past work on the diverse sequences of
human milk oligosaccharides (HMOs) has been focused mainly on the highly abundant …