[HTML][HTML] Changing perspectives from oxidative stress to redox signaling—extracellular redox control in translational medicine

P Loreto Palacio, JR Godoy, O Aktas, EM Hanschmann - Antioxidants, 2022 - mdpi.com
Extensive research has changed the understanding of oxidative stress that has been linked
to every major disease. Today we distinguish oxidative eu-and distress, acknowledging that …

Inflammation resolution in environmental pulmonary health and morbidity

JM Marzec, SS Nadadur - Toxicology and applied pharmacology, 2022 - Elsevier
Inflammation and resolution are dynamic processes comprised of inflammatory activation
and neutrophil influx, followed by mediator catabolism and efferocytosis. These critical …

Nano-bioengineered sensing technologies for real-time monitoring of reactive oxygen species in in vitro and in vivo models

R Kumari, DS Dkhar, S Mahapatra, R Kumar… - Microchemical …, 2022 - Elsevier
Reactive oxygen species are produced as a by-product of the animal cellular metabolism
and play an important function in cell signaling. Uncontrolled reactive oxygen species …

[HTML][HTML] Antioxidants as therapeutic agents in acute respiratory distress syndrome (ARDS) treatment—From mice to men

A von Knethen, U Heinicke, V Laux, MJ Parnham… - Biomedicines, 2022 - mdpi.com
Acute respiratory distress syndrome (ARDS) is a major cause of patient mortality in intensive
care units (ICUs) worldwide. Considering that no causative treatment but only symptomatic …

Wound healing activity of aqueous dispersion of fullerene C60 produced by “green technology”

NN Shershakova, SM Andreev, AA Tomchuk… - … , Biology and Medicine, 2023 - Elsevier
In addition to exhibited antioxidant and anti-inflammatory activity, fullerene C60 is a
promising wound healing agent. An important stage in the production of fullerene-based …

[HTML][HTML] Exacerbation of Elastase-Induced Emphysema via increased oxidative stress in metallothionein-knockout mice

KI Tanaka, S Shiota, O Sakakibara, M Shimoda… - Biomolecules, 2022 - mdpi.com
Although the pathogenesis of chronic obstructive pulmonary disease (COPD) is not yet fully
understood, recent studies suggest that the disruption of the intracellular balance of …

[HTML][HTML] Redox regulation in aging lungs and therapeutic implications of antioxidants in COPD

H Kiyokawa, Y Hoshino, K Sakaguchi, S Muro, J Yodoi - Antioxidants, 2021 - mdpi.com
Mammals, including humans, are aerobic organisms with a mature respiratory system to
intake oxygen as a vital source of cellular energy. Despite the essentiality of reactive oxygen …

BALB/c and C57BL/6 mice differ in oxidant and antioxidant responses in innate and adaptive immune cells in an asthma model induced by cockroach allergens

LA Al-Kharashi, SA Alqarni, SF Ahmad… - International …, 2023 - Elsevier
Asthma is a complex and heterogenous disease affected by a multitude of factors. Several
phenotypes of asthma exist which are influenced by various molecular mechanisms that …

[HTML][HTML] Identification of novel diclofenac acid and naproxen bearing hydrazones as 15-LOX inhibitors: Design, synthesis, in vitro evaluation, cytotoxicity, and in silico …

A Sardar, S Daud, BA Shah, W Shahid, M Ashraf… - Arabian Journal of …, 2022 - Elsevier
Inflammation is the immune system's adaptive response to tissue dysfunction or homeostatic
imbalance, inducing fever, pain, physiological and biochemical changes via the …

The ACE2 activator diminazene aceturate ameliorates colitis by repairing the gut-vascular barrier in mice

C Zhang, X Cao, H Wang, Z Li, Y Zhang - Microvascular Research, 2023 - Elsevier
Alleviating vascular barrier injury improves colitis. Angiotensin converting enzyme
2/angiotensin 1-7/Mas receptor (ACE2/Ang1-7/MasR) axis-related drugs have various …