Nasopharyngeal carcinoma: an evolving paradigm

KCW Wong, EP Hui, KW Lo, WKJ Lam… - Nature reviews Clinical …, 2021 - nature.com
The past three decades have borne witness to many advances in the understanding of the
molecular biology and treatment of nasopharyngeal carcinoma (NPC), an Epstein–Barr virus …

[HTML][HTML] The global landscape of EBV-associated tumors

C Shannon-Lowe, A Rickinson - Frontiers in oncology, 2019 - frontiersin.org
Epstein-Barr virus (EBV), a gamma-1 herpesvirus, is carried as a life-long asymptomatic
infection by the great majority of individuals in all human populations. Yet this seemingly …

Hypoxia-induced epithelial-mesenchymal transition in cancers: HIF-1α and beyond

SY Tam, VWC Wu, HKW Law - Frontiers in oncology, 2020 - frontiersin.org
Metastasis is the main cause of cancer-related mortality. Although the actual process of
metastasis remains largely elusive, epithelial-mesenchymal transition (EMT) has been …

Epstein–Barr virus infection and nasopharyngeal carcinoma

SW Tsao, CM Tsang, KW Lo - … Transactions of the …, 2017 - royalsocietypublishing.org
Epstein–Barr virus (EBV) is associated with multiple types of human cancer, including
lymphoid and epithelial cancers. The closest association with EBV infection is seen in …

Epigenetic regulation of the innate immune response to infection

Q Zhang, X Cao - Nature Reviews Immunology, 2019 - nature.com
Innate immune cells have complex signalling pathways for sensing pathogens and initiating
innate immune responses against infection. These pathways are tightly regulated at different …

Epstein–Barr virus-associated lymphomas

C Shannon-Lowe, AB Rickinson… - … Transactions of the …, 2017 - royalsocietypublishing.org
Epstein–Barr virus (EBV), originally discovered through its association with Burkitt
lymphoma, is now aetiologically linked to a remarkably wide range of lymphoproliferative …

The role of Epstein–Barr virus in epithelial malignancies

SW Tsao, CM Tsang, KF To, KW Lo - The Journal of pathology, 2015 - Wiley Online Library
The close association of Epstein–Barr virus (EBV) infection with non‐keratinizing
nasopharyngeal carcinomas and a subset of gastric carcinomas suggests that EBV infection …

Etiological factors of nasopharyngeal carcinoma

SW Tsao, YL Yip, CM Tsang, PS Pang, VMY Lau… - Oral oncology, 2014 - Elsevier
Nasopharyngeal carcinoma (NPC) is a common disease among southern Chinese. The
major etiological factors proposed for NPC pathogenesis include genetic susceptibility …

[HTML][HTML] Translational genomics of nasopharyngeal cancer

CM Tsang, VWY Lui, JP Bruce, TJ Pugh… - Seminars in cancer biology, 2020 - Elsevier
Nasopharyngeal carcinoma (NPC), also named the Cantonese cancer, is a unique cancer
with strong etiological association with infection of the Epstein-Barr virus (EBV). With …

[HTML][HTML] The role of Epstein–Barr virus in nasopharyngeal carcinoma

ZY Su, PY Siak, CO Leong, SC Cheah - Frontiers in microbiology, 2023 - frontiersin.org
Nasopharyngeal carcinoma (NPC) is a metastasis-prone malignancy closely associated
with the Epstein–Barr virus (EBV). Despite ubiquitous infection of EBV worldwide, NPC …