Ketamine and ketamine metabolite pharmacology: insights into therapeutic mechanisms
Ketamine, a racemic mixture consisting of (S)-and (R)-ketamine, has been in clinical use
since 1970. Although best characterized for its dissociative anesthetic properties, ketamine …
since 1970. Although best characterized for its dissociative anesthetic properties, ketamine …
Extent of illicit drug use and dependence, and their contribution to the global burden of disease
L Degenhardt, W Hall - The Lancet, 2012 - thelancet.com
This paper summarises data for the prevalence, correlates, and probable adverse health
consequences of problem use of amphetamines, cannabis, cocaine, and opioids. We …
consequences of problem use of amphetamines, cannabis, cocaine, and opioids. We …
Major physical and psychological harms of methamphetamine use
S Darke, S Kaye, R McKetin… - Drug and alcohol review, 2008 - Wiley Online Library
Issues. The major physical and psychological health effects of methamphetamine use, and
the factors associated with such harms. Approach. Comprehensive review. Key Findings …
the factors associated with such harms. Approach. Comprehensive review. Key Findings …
The methamphetamine problem in the United States
R Gonzales, L Mooney… - Annual review of public …, 2010 - annualreviews.org
Significant public health problems associated with methamphetamine (MA) production and
use in the United States have emerged over the past 25 years; however, there has been …
use in the United States have emerged over the past 25 years; however, there has been …
Metabolism and metabolomics of ketamine: a toxicological approach
RJ Dinis-Oliveira - Forensic sciences research, 2017 - academic.oup.com
Ketamine is a phencyclidine derivative and a non-competitive antagonist of N-methyl-D-
aspartate (NMDA) receptor for which glutamate is the full agonist. It produces a functional …
aspartate (NMDA) receptor for which glutamate is the full agonist. It produces a functional …
Stroke and methamphetamine use in young adults: a review
Background Methamphetamine use and stroke are significant public health problems.
Strokes among people aged below 45 years are much less common than in older age …
Strokes among people aged below 45 years are much less common than in older age …
Methamphetamine and cardiovascular pathology: a review of the evidence
Aims To examine the literature pertaining to the cardiovascular effects of methamphetamine
and discuss the implications for methamphetamine users. Methods Relevant literature was …
and discuss the implications for methamphetamine users. Methods Relevant literature was …
Pharmacologic mechanisms of crystal meth
SJ Kish - Cmaj, 2008 - Can Med Assoc
Crystal meth is a form of the stimulant drug methamphetamine that, when smoked, can
rapidly achieve high concentrations in the brain. Methamphetamine causes the release of …
rapidly achieve high concentrations in the brain. Methamphetamine causes the release of …
Rates, characteristics and circumstances of methamphetamine‐related death in Australia: a national 7‐year study
Aims To (1) assess trends in the number and mortality rates of methamphetamine‐related
death in Australia, 2009–15;(2) assess the characteristics and the cause, manner and …
death in Australia, 2009–15;(2) assess the characteristics and the cause, manner and …